Essentials of pharmacology for dentistry / K.D. Tripathi.

Include index.

1. Introduction, Routes of Drug Administration 3
Introduction 3
Routes of Drug Administration 5
2. Pharmacokinetics 10
Drug Transport 11
Drug Absorption 14
Drug Distribution 16
Drug Biotransformation (Metabolism) 20
Drug Excretion 25
Kinetics of Elimination 26
3. Pharmacodynamics 31
Principles of Drug Action 31
Mechanism of Drug Action 31
Combined Effect of Drugs 45
Drug Dosage 48
Factors Modifying Drug Action 50
4. Adverse Drug Effects 56
5. Drugs Acting on Autonomic Nervous System 67
(General Considerations, Cholinergic and Anticholinergic Drugs) General Considerations 67
Cholinergic Drugs (Cholinomimetic, Parasympathomimetic) 72
Anticholinesterases 74
Anticholinergic Drugs (Parasympatholytic) 76
Drugs Acting on Autonomic Ganglia 80
6. Drugs Acting on Autonomic Nervous System 81
(Adrenergic and Antiadrenergic Drugs) Adrenergic Transmission 81
Adrenergic Drugs (Sympathomimetics) 83
Antiadrenergic Drugs (Adrenergic Receptor Antagonists) 90
7. Autacoids and Related Drugs 98
Histamine 98
H1 Antagonists (Conventional Antihistaminics) 101
5-hydroxytryptamine (5-HT, Serotonin) 105
Drug Therapy of Migraine 107
Prostaglandins and Leukotrienes (Eicosanoids) 109
Platelet Activating Factor (PAF) 115
8. General Anaesthetics and Skeletal Muscle Relaxants 117
General Anaesthetics 117
Preanaesthetic Medication 125
Skeletal Muscle Relaxants 126
9. Drugs Acting on Central Nervous System 133
(Sedative-Hypnotics, Alcohols, Antiepileptics and Antiparkinsonian Drugs)
Sedative-hypnotics 133
Ethyl Alcohol (Ethanol) 139
Antiepileptic Drugs 143
Antiparkinsonian Drugs 149
10. Drugs Acting on Central Nervous System 155
(Psychopharmacological Agents)
Psychopharmacological Agents 155
Antipsychotic Drugs (Neuroleptics) 156
Antimanic (Mood Stabilizing) Drugs 160
Antidepressant Drugs 163
Antianxiety Drugs 168
11. Cardiovascular Drugs 171
(Drugs Affecting Renin-Angiotensin System, Calcium Channel Blockers,
Drugs for Hypertension, Angina Pectoris and Myocardial Infarction)
Angiotensin 171
Angiotensin Converting Enzyme Inhibitors 173
Calcium Channel Blockers 176
Antihypertensive Drugs 178
Antianginal Drugs 183
Drug Therapy in Myocardial Infarction 188
viii Essentials of Pharmacology for Dentistry
12. Cardiovascular Drugs 190
(Drugs for Heart Failure and Cardiac Arrhythmia)
Cardiac Glycosides 190
Treatment of Congestive Heart Failure 195
Antiarrhythmic Drugs 197
13. Drugs Acting on Kidney 203
Relevant Physiology of Urine Formation 203
Diuretics 205
Antidiuretics 212
14. Hormones and Related Drugs 215
(Anterior Pituitary Hormones, Antidiabetic Drugs, Corticosteroids)
Introduction 215
Anterior Pituitary Hormones 216
Antidiabetic Drugs 219
Insulin 220
Oral Hypoglycaemic Drugs 224
Corticosteroids 228
15. Hormones and Related Drugs 235
(Sex Hormones, Contraceptives, Drugs Acting on Uterus) Androgens (Male Sex Hormones) 235
Estrogens 237
Progestins 239
Hormonal Contraceptives 241
Uterine Stimulants (Oxytocics, Abortifacients) 243
Uterine Relaxants (Tocolytics) 245
16. Hormones and Related Drugs 246
(Thyroid Hormone and Thyroid Inhibitors, Hormones Regulating Calcium Balance)
Thyroid Hormone 246
Thyroid Inhibitors 249
Hormones Regulating Calcium 250
17. Drugs Affecting Blood 256
Haematinics 256
Coagulants 260
Anticoagulants 264
Fibrinolytics (Thrombolytics) 268
Antifibrinolytics 269
Antiplatelet Drugs (Antithrombotic Drugs) 269
Hypolipidaemic Drugs 271
18. Drugs for Gastrointestinal Disorders 274
Drugs for Peptic Ulcer 274
Antiemetics 280
Treatment of Gastroesophageal Reflux Disease 284
Laxatives (Aperients, Purgatives, Cathartics) 285
Treatment of Diarrhoeas 288
19. Drugs for Respiratory Disorders 291
Drugs for Cough 291
Drugs for Bronchial Asthma 292
20. Vitamins 299
Fat-soluble Vitamins 300
Water-soluble Vitamins 301
21. Anticancer and Immunosuppressant Drugs 305
Anticancer Drugs 305
Immunosuppressant Drugs 313
22. Antirheumatoid and Antigout Drugs 317
Antirheumatoid Drugs 317
Drugs Used in Gout 319
23. Nonsteroidal Antiinflammatory Drugs and Antipyretic-Analgesics 325
Analgesic/NSAIDs in Dentistry 339
24. Opioid Analgesics and Antagonists 341
Opioid Analgesics 341
Complex Action Opioids and Opioid Antagonists 350
25. Local Anaesthetics 354
Uses and Techniques of Local Anaesthesia 361
Local Anaesthesia in Dentistry 362
26. Antimicrobial Drugs: General Considerations 364
Drug Resistance 367
Superinfection 369
Choice of an Antimicrobial Agent 370
Combined Use of Antimicrobials 373
Prophylactic Use of Antimicrobials 375
27. Sulfonamides, Cotrimoxazole, Quinolones and Nitroimidazoles 379
Sulfonamides 379
Cotrimoxazole 381
Quinolones 382
Nitroimidazoles 387
28. Beta-Lactam Antibiotics 390
Penicillins 390
Cephalosporins 399
Monobactams 404
Carbapenems 404
29. Tetracyclines, Chloramphenicol and Aminoglycoside Antibiotics 405
Tetracyclines 405
Chloramphenicol 410
Aminoglycoside Antibiotics 413
30. Macrolide and Other Antibacterial Antibiotics 420
Macrolide Antibiotics 420
Miscellaneous (Lincosamide, Glycopeptide, Oxazolidinone, Polypeptide) Antibiotics 423
Urinary Antiseptics 427
31. Antitubercular and Antileprotic Drugs 428
Antitubercular Drugs 428
Treatment of Tuberculosis 432
Antileprotic Drugs 435
Multidrug Therapy of Leprosy 436
32. Antifungal and Antiviral Drugs 438
Antifungal Drugs 438
Antiviral Drugs 444
Treatment of HIV Infection 449
Prophylaxis of HIV Infection 450
33. Antiprotozoal and Anthelmintic Drugs 452
Antimalarial Drugs 452
Antiamoebic Drugs 460
Drugs for Giardiasis and Drugs for Trichomoniasis 462
Drugs for Leishmaniasis 463
Anthelmintic Drugs 463
34. Antiseptics, Disinfectants and Other Locally Acting Drugs 469
Antiseptics and Disinfectants 469
Locally Acting Drugs 476
35. Drugs and Aids with Specific Application in Dental Disorders 477
Antiplaque and Antigingivitis Agents 477
Antibiotics in Periodontal Disease 479
Anticaries Drugs 480
Desensitizing Agents 483
Obtundants 484
Mummifying Agents 484
Bleaching Agents 485
Disclosing Agents 485
Dentifrices 486
36. Drug Interactions 488
Mechanisms of Drug Interactions 489
Drug Interactions in Dentistry 491
Index 495