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Studies on experimental toxicology and pharmacology /

Studies on experimental toxicology and pharmacology / Stephen M. Roberts, James P. Kehrer and Lars-Oliver Klotz, editors. - xvi, 498 pages : illustrations (black and white, and colour) ; 20 cm

Includes bibliographical references and index.

Part I. Toxicological Mechanisms and Evaluation of Oxidative Stress --
A historical perspective on oxidative stress and intracellular redox control --
An overview of free radicals as causes and consequences of toxicity --
Oxidants, radicals, free radicals, and other bad stuff in mechanisms of toxicity --
Lipid oxidation --
Protein oxidation and toxicology --
Oxidative stress and DNA damage association with carcinogenesis: A truth or a myth? --
Glutathione and thiols --
Reactive oxygen species as initiators and mediators of cellular signaling processes --
Role of oxidative stress in the process of carcinogenesis --
Part II. Agents that produce toxicity? mechanisms and therapeutic interventions --
Isolation of murine adult bone marrow and fetal liver cells for mechanistic assessment of hematotoxicity caused by organic solvents --
Oxidative stress and ethanol toxicity --
Pharmaceutical agents --
Insecticides and herbicides --
Health effects of indoor air pollution due to cooking with biomass fuel --
Outdoor pollutants --
Oxidative Stress and the Inorganic Carcinogens --
UV-induced signaling: Role of reactive oxygen species --
Nanomaterials --
Chemical warfare agents --
Part III. Special topics --
On the biochemistry of antioxidants? current aspects.-Prevention of age-related diseases? Effects of antioxidant supplements --
The neural progenitor cell (NPC) niche in the adult brain provides a target for neurotoxicity? a potential Adverse Outcome Pathway for ROS-induced NPC dysfunction with higher sensitivity during aging. --
Oxygen toxicity: From cough to convulsion --
Oxidative stress in reproductive toxicology --
Toxicogenomics-based assessment of xenobiotic-induced oxidative stress --
Aquatic and marine biology.

9783319190952

2015951628


Free radicals (Chemistry)--Pathophysiology.
Toxicology.
Antioxidants--Health aspects.

615.9 / S