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Preclinical drug disposition : a laboratory handbook /

Tse, Francis L. S.

Preclinical drug disposition : a laboratory handbook / Francis L.S. Tse, James M. Jaffe. - xi, 163 pages : illustrations ; 24 cm. - Drugs and the pharmaceutical sciences ; v. 46 .

Includes bibliographical references and index.

Ch. 1 Introduction --
Ch. 2 Use of radioactivity in drug disposition studies --
Ch. 3 The rat --
Ch. 4. The Mouse --
Ch. 5 --
The dog --
Ch. 6 The rabbit --
Ch. 7 The monkey --
Ch. 8 Data interpretation.

Suitable for researchers and students in pharmacology and related fields, this title explains the techniques for investigating the absorption, distribution, metabolism, and excretion of test compounds using laboratory animals. It describes types of experiments, study design, and animal preparation and maintenance.

0824785002 (acidfree paper)

90028573


Drugs--Metabolism--Handbooks, manuals, etc.
Pharmacokinetics--Handbooks, manuals, etc.
Pharmacology, Experimental--Handbooks, manuals, etc.

RM301.55 / .T78 1991

615.7 / T.F.P