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Controlled drug delivery : challenges and strategies /

Controlled drug delivery : challenges and strategies / Kinam Park, editor, Purdue university. - xvii, 629 pages : illustrations ; 24 cm - ACS professional reference book . - ACS professional reference book .

Includes bibliographical references and index.

CONTROLLED DRUG DELIVERY: PAST, PRESENT, AND FUTURE -- INTRACELLULAR DELIVERY AND TARGETING -- 2. Intracellular Delivery of Peptides and Proteins -- 3. DNA Delivery Vectors for Somatic Cell Gene Therapy -- 4. Targetable Polymeric Drugs -- 5. Particle Engineering of Biodegradable Colloids for Site-Specific Drug Delivery -- 6. Site-Specific Drug Delivery in the Gastrointestinal Tract -- SELF-REGULATED DRUG DELIVERY -- 7. Feedback-Controlled Drug Delivery -- 8. Stimuli-Sensitive Drug Delivery -- 9. Sensocompatibility: Design Considerations for Biosensor-Based Drug Delivery Systems -- DELIVERY OF PEPTIDE AND PROTEIN DRUGS -- 10. Formulation of Proteins and Peptides -- 11. Stability of Peptides and Proteins -- 12. Peptide, Protein, and Vaccine Delivery from Implantable Polymeric Systems -- 13. Oral Immunization Using Microparticles -- 14. Peptide and Protein Delivery for Animal Health Applications -- TISSUE ENGINEERING AND GENE THERAPY -- 15. Protein Delivery by Microencapsulated Cells -- 16. Tissue Engineering: Integrating Cells and Materials To Create Functional Tissue Replacements -- 17. Drug Delivery Using Genetically Engineered Cell Implants -- 18. Ribozymes as Antiviral Agents -- NEW BIOMATERIALS FOR DRUG DELIVERY -- 19. Pseudo-Poly(amino acid)s: Examples for Synthetic Materials Derived from Natural Metabolites -- 20. Transductional Protein-Based Polymers as New Controlled-Release Vehicles -- 21. Synthetically Designed Protein Polymer Biomaterials -- 22. Biological Effects of Polymeric Drugs -- 23. New Biodegradable Polymers for Medical Applications: Elastomeric Poly(phosphoester-urethane)s -- 24. "Intelligent" Polymers -- MODELING OF CONTROLLED DRUG DELIVERY -- 25. Modeling of Self-Regulating Oscillatory Drug Delivery -- 26. Modeling Studies of Future Controlled-Release Devices -- 27. Computer Dynamics Simulation of Controlled Release -- REGULATORY ISSUES -- 28. Food and Drug Regulations for Controlled-Release Dosage Forms -- 29. Pharmacodynamic and Pharmacokinetic/ Considerations in Controlled Drug Delivery

0841234183 (alk. paper)

96051016


Drug delivery systems.
Drugs--Dosage forms.

RS199.5 / .C66 1997

615.6 / C.