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Methods for the discovery and characterization of G protein-coupled receptors /

Methods for the discovery and characterization of G protein-coupled receptors / edited by Craig W. Stevens. - xiii, 428 pages. : illustrations. ; 26 cm. - Neuromethods ; 60 . - Neuromethods ; 60. .

Includes bibliographical references and index.

In silico identification of novel G protein-coupled receptors / Alternative pre-mRNA splicing of G protein-coupled receptors / Detecting polymorphisms in G protein-coupled receptor genes / Regulation of the transcription of G protein-coupled receptor genes / Deciphering the evolution of G protein-coupled receptors in vertebrates / New approach to visualize endogenously expressed G protein-coupled receptors in tissues and living cells / Posttranslational regulation of G protein-coupled receptors / Discovering G protein-coupled receptor motifs mediating export from the endoplasmic reticulum / Identifying G protein-coupled receptor escorts, chaperones, and intracellular tethers regulating receptor density at the cell surface / Novel method for determining the kinetics of G protein-coupled receptor plasma membrane expression / Characterizing the pharmacology of G protein-coupled receptors in transfected cell lines / Novel assay technologies for the discovery of G protein-coupled receptor drugs / Discovering cell type-specific patterns of G protein-coupled receptor phosphorylation / Quantifying allosteric modulation of G protein-coupled receptors / Experimental designs for the study of receptor-receptor interactions / Elucidating agonist-selective mechanisms of G protein-coupled receptor desensitization / Detecting the role of arrestins in G protein-coupled receptor regulation / Characterizing molecular mobility and membrane interactions of G protein-coupled receptors / Using RNA interference to downregulate G protein-coupled receptors / Upregulating G protein-coupled receptors with receptor antagonists /

9781617791789 (alk. paper) 1617791784 (alk. paper)

2011930757


G proteins.
G proteins--Receptors.
GTP-Binding Proteins.
Receptors, G-Protein-Coupled.

QP552.G16 / M48 2011

572.696 / M