MARC details
| 000 -LEADER |
|---|
| fixed length control field |
04665cam a22004817i 4500 |
| 001 - CONTROL NUMBER |
|---|
| control field |
18478484 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20201006100106.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
150203s2015 ne a b 001 0 eng |
| 010 ## - LIBRARY OF CONGRESS CONTROL NUMBER |
|---|
| LC control number |
2015932534 |
| 016 7# - NATIONAL BIBLIOGRAPHIC AGENCY CONTROL NUMBER |
|---|
| Record control number |
101664503 |
| Source |
DNLM |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9780128014110 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
0128014113 |
| 035 ## - SYSTEM CONTROL NUMBER |
|---|
| System control number |
(OCoLC)ocn905638680 |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
NLM |
| Language of cataloging |
eng |
| Transcribing agency |
NLM |
| Modifying agency |
YDXCP |
| -- |
LTSCA |
| -- |
NLE |
| -- |
OCLCF |
| -- |
CDX |
| -- |
DLC |
| Description conventions |
rda |
| 042 ## - AUTHENTICATION CODE |
|---|
| Authentication code |
nlmcopyc |
| -- |
lccopycat |
| 050 00 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
RM301.5 |
| Item number |
.T46 2015 |
| 060 00 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER |
|---|
| Classification number |
2015 G-769 |
| 060 10 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER |
|---|
| Classification number |
QV 38 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
615.7 |
| Edition number |
23 |
| Item number |
L.T.E |
| 100 0# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Thorsteinn Loftsson. |
| Relator term |
author. |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Essential pharmacokinetics : |
| Remainder of title |
a primer for pharmaceutical scientists / |
| Statement of responsibility, etc |
Thorsteinn Loftsson. |
| 264 #1 - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc |
Amsterdam ; |
| -- |
Boston : |
| Name of publisher, distributor, etc |
Elsevier/AP, Academic Press is an imprint of Elsevier, |
| Date of publication, distribution, etc |
[2015] |
| 264 #4 - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Date of publication, distribution, etc |
©2015. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
vii, 170 pages : |
| Other physical details |
illustrations ; |
| Dimensions |
23 cm |
| 336 ## - CONTENT TYPE |
|---|
| Source |
rdacontent |
| Content type term |
text |
| 337 ## - MEDIA TYPE |
|---|
| Source |
rdamedia |
| Media type term |
unmediated |
| 338 ## - CARRIER TYPE |
|---|
| Source |
rdacarrier |
| Carrier type term |
volume |
| 500 ## - GENERAL NOTE |
|---|
| General note |
pharmacy bookfair2016 |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc |
Includes bibliographical references and index. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
<br/>Front Cover -- Essential Pharmacokinetics -- Copyright Page -- Contents -- Preface -- 1 Introduction -- 1.1 Some Basic Concepts -- 1.2 Pharmacokinetic Models -- 1.3 Population Pharmacokinetics -- References -- 2 Basic Concepts of Pharmacokinetics -- 2.1 One-Compartment Open Model -- 2.1.1 IV Bolus Injection -- 2.1.2 IV Infusion -- 2.2 Two-Compartment Open Model -- 2.2.1 IV Bolus Injection -- 2.2.2 IV Infusion -- 2.3 Three-Compartment Open Model -- 2.4 Pharmacokinetics of Drug Absorption -- 2.4.1 One-Compartment Open Model with Zero-Order Drug Absorption -- 2.4.2 One-Compartment Open Model with First-Order Drug Absorption 2.4.3 One-Compartment Open Model with Urine Sample Collection2.4.4 Two-Compartment Open Model with First-Order Drug Absorption -- 2.4.5 Flip-Flop Pharmacokinetics -- 2.5 Bioavailability -- 2.6 Drug Distribution, Protein Binding, and Clearance -- 2.6.1 Protein Binding -- 2.6.2 Clearance -- 2.7 Multiple-Dose Regimens -- 2.7.1 Multiple-Dosage by IV Bolus Injection and One-Compartment Open Model -- 2.7.2 Multiple-Dosage by Oral Administration and One-Compartment Open Model -- 2.7.3 Loading Dose -- 2.8 Nonlinear Pharmacokinetics -- 2.8.1 Michaelis-Menten Equation -- 2.9 Drug Metabolism 2.10 Drug Permeation Through Biomembranes and Drug Transporters2.10.1 Biomembranes -- 2.10.2 Passive Transport Through Mucosa -- References -- 3 Physicochemical Properties and Pharmacokinetics -- 3.1 Lipinski's Rule of Five -- 3.2 The Biopharmaceutics Classification System -- 3.3 The Biopharmaceutics Drug Disposition Classification System -- 3.4 Metabolizability, Soft Drugs, and Prodrugs -- 3.5 Pharmacokinetics of Excipients -- References -- 4 Drug Pharmacokinetics After Alternative Routes of Administration -- 4.1 Fentanyl Transdermal Patch -- 4.2 Estradiol Sublingual Tablets -- 4.3 Diazepam Suppositories 4.4 Midazolam Nasal Spray4.5 Pulmonary Delivery (Inhalation) and Subcutaneous Injection of Insulin -- 4.6 Topical Delivery of Dexamethasone to the Eye -- References -- 5 Pharmacologic Response and Drug Dosage Adjustments -- 5.1 Therapeutic Drug Monitoring -- 5.2 Dosage Adjustments -- 5.3 Pharmacodynamics -- 6 The Effect of Food and Excipients on Drug Pharmacokinetics -- References |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists is an introduction to the concepts of pharmacokinetics intended for graduate students and new researchers working in the pharmaceutical sciences. This book describes the mathematics used in the mammillary model as well as the application of pharmacokinetics to pharmaceutical product development, and is useful as both a self-study and classroom resource. Content coverage includes detailed discussions of common models and important pharmacokinetic concepts such as biological half-life, clearance, excretion, multiple dosage regimens and more. Numerous equations, practical examples and figures are incorporated to clearly illustrate the theoretical background of pharmacokinetic behavior of drugs and excipients. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Pharmacokinetics. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Biochemistry. |
| 650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Pharmacokinetics. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Biochemistry. |
| Source of heading or term |
fast |
| Authority record control number |
(OCoLC)fst00831961 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Pharmacokinetics. |
| Source of heading or term |
fast |
| Authority record control number |
(OCoLC)fst01060250 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| Materials specified |
Abstract |
| Uniform Resource Identifier |
<a href="http://repository.fue.edu.eg/xmlui/handle/123456789/1815">http://repository.fue.edu.eg/xmlui/handle/123456789/1815</a> |
| 906 ## - LOCAL DATA ELEMENT F, LDF (RLIN) |
|---|
| a |
7 |
| b |
cbc |
| c |
copycat |
| d |
2 |
| e |
ncip |
| f |
20 |
| g |
y-gencatlg |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Books |