MARC details
| 000 -LEADER |
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| fixed length control field |
03139nam a22003137i 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20190424114329.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
190424s2018 ua djk||frbm| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
FUE |
| Description conventions |
rda |
| 041 ## - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
eng |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Edition number |
23 |
| Classification number |
542.85 |
| Item number |
M.E.A |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Morgan, Eman Mohamed, |
| Relator term |
author. |
| 245 12 - TITLE STATEMENT |
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| Title |
Analytical Study Of Some Drug Containing Carboxylic Acid Derivatives / |
| Statement of responsibility, etc |
Eman Mohamed Morgan, SupervisorBy, Mohamed Abdel Kawy, Hayam Mahmoud Lotfy, Yasmein Mohamed Fayes.. |
| 246 ## - VARYING FORM OF TITLE |
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| Title proper/short title |
دراسة تحليلية على بعض العقاقيرالتي تحتوي على مشتقات مجموعة الكاربوكسيل |
| 264 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
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| Date of publication, distribution, etc |
2018. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
xxiii, 5, 241 pages. : |
| Other physical details |
illustration. ; |
| Dimensions |
25 cm. |
| 336 ## - CONTENT TYPE |
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| Source |
rdacontent |
| Content type term |
text |
| 337 ## - MEDIA TYPE |
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| Source |
rdamedia |
| Media type term |
unmediated |
| 338 ## - CARRIER TYPE |
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| Source |
rdacarrier |
| Carrier type term |
volume |
| 502 ## - DISSERTATION NOTE |
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| Dissertation note |
Thesis (M.Sc.) – Cairo University. Faculty of Pharmacy. Department of Analytical Chemistry.<br/> |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc |
Includes bibliographical references.<br/> |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc |
This thesis is concerned with the quantitative determination of some drugs containing carboxylic acid derivatives; namely Valaciclovir Hydrochloride and Trimebutine Maleate in their pure powdered form, in presence of their degradation products and application on pharmaceutical formulations.<br/>In this thesis; different analytical techniques were adopted, namely, UV-spectrophotometric, visible spectrophotometric, chromatographic and electrochemical methods for the determination of the previously mentioned compounds in their pure powder, laboratory prepared mixtures and pharmaceutical formulations.<br/>In part I; General introduction and literature review of valaciclovir hydrochloride (VAL) and its active metabolite aciclovir (ACI) were described. This part described also the quantitative determination of VAL in pure form or dosage form using UV-spectrophotometry including six methods namely, dual wavelength (DW), induced dual wavelength (IDW), ratio difference (RD), constant center coupled with spectrum subtraction spectrophotometric method (CC-SS), the first derivative of the ratio spectra (DD1) and mean centering of ratio spectra (MCR), visible-spectrophotometric method, chromatographic (RP-UPLC method and TLC-densitometry) methods and electrochemical method (ISE). <br/>In part II; General introduction and literature review of trimebutine maleate (TM) were described. Then different analytical methods were described for the determination of the studied drugs in their pure form or dosage form including four spectrophotometric methods namely, dual wavelength (DW), second derivative (D2), ratio difference (RD) and constant center coupled with spectrum subtraction spectrophotometric method (CC-SS) and chromatographic (RP-HPLC and TLC-densitometry) methods. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
Text in English, abstracts in English and Arabic.<br/> |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Analytical chemistry series. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Fayez, Yasmin Mohamed, |
| Relator term |
Supervisor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Lotfy, Hayam Mahmoud , |
| Relator term |
Supervisor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Abdelkawy, Mohamed, |
| Relator term |
Supervisor. |
| 710 #2 - ADDED ENTRY--CORPORATE NAME |
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| Corporate name or jurisdiction name as entry element |
Cairo University. |
| Subordinate unit |
Faculty of Pharmacy. |
| -- |
Department of Analytical Chemistry. |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Thesis |