MARC details
| 000 -LEADER |
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| fixed length control field |
04302ntm a2200313 i 4500 |
| 001 - CONTROL NUMBER |
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| control field |
12102116 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20211024132905.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
150118s2020 ua a f bm 000 0 eng | |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
EG-EULC |
| Transcribing agency |
EG-EULC |
| Description conventions |
rda |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| Language code of summary or abstract/overprinted title or subtitle |
ara |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
615.1 |
| Item number |
B.D.E |
| Edition number |
22 |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
El Bohy, Doaa Mohamed Salah Diab. |
| 9 (RLIN) |
33872 |
| Relator term |
author. |
| 245 10 - TITLE STATEMENT |
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| Title |
Effect of pantoprazole and esmoprazole on the cyclosporine blood concentration in a kideny transplant recipient / |
| Statement of responsibility, etc |
Doaa Mohamed Salah Eldian Diab El Bohy, (M.Sc. pharm. Sci. clinical pharmacy, 2012, assistant lecturer of Clinical pharmacy , faculty of pharmacy, Future university); Supervisors Manal Hamed El Hamamsy, (Ph. D. Professor of Clinical pharmacy, faculty of pharmacy, Ain Shams University), Magdy Mohamed El Sharkawy, M.D., (Professor of internal medicine & Nephrology, faculty of medicine, Ain Shams University), Soheir Abo El-Azm Diab, Ph. D., (professor of pharmacology, faculty of medicine, Cairo University), Waleed Ahmed Bchari, M.D., (Associate Professor of internal medicine & Nephrology, faculty of medicine, Ain Shams University), Sara Mahmoud Shahin, Ph. D., (Associate Professor of Clinical pharmacy, faculty of pharmacy, Ain Shams University).<br/> |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
تأثير عقاري البانتوبرازول و الازموبرازول على تركيز عقار السيكلوسبورن في دم مرضى زرع الكلي |
| 264 #1 - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Date of publication, distribution, etc |
2020 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
96 pages, 3 pages : |
| Other physical details |
illustrations (some color) ; |
| Dimensions |
24 cm |
| 336 ## - CONTENT TYPE |
|---|
| Source |
rdacontent |
| Content type term |
text |
| 337 ## - MEDIA TYPE |
|---|
| Source |
rdamedia |
| Media type term |
unmediated |
| 338 ## - CARRIER TYPE |
|---|
| Source |
rdacarrier |
| Carrier type term |
volume |
| 500 ## - GENERAL NOTE |
|---|
| General note |
Supervisors Manal Hamed El Hamamsy, (Ph. D. Professor of Clinical pharmacy, faculty of pharmacy, Ain Shams University), Magdy Mohamed El Sharkawy, M.D., (Professor of internal medicine & Nephrology, faculty of medicine, Ain Shams University), Soheir Abo El-Azm Diab, Ph. D., (professor of pharmacology, faculty of medicine, Cairo University), Waleed Ahmed Bchari, M.D., (Associate Professor of internal medicine & Nephrology, faculty of medicine, Ain Shams University), Sara Mahmoud Shahin, Ph. D., (Associate Professor of Clinical pharmacy, faculty of pharmacy, Ain Shams University).<br/> |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (Ph.D.)-Ain Shams university, Faculty of pharmacy, Department of Clinical pharmacy, 2020. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc |
Includes bibliographical references. |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc |
Renal allograft survival requires multiple immunosuppressive drugs. This strategy<br/>may lead to gastric complications that necessitate gastro-protective medications,<br/>notably, proton pump inhibitors (PPI). This study aimed to compare the influence<br/>of pantoprazole and esomeprazole on serum cyclosporine trough levels (C0) in<br/>renal transplant recipients (RTR). A prospective, parallel, open-label trial was<br/>conducted on 47 adult RTR receiving cyclosporine doses adjusted to attain trough<br/>concentrations of 100 to 150 μg/L, mycophenolate mofetil (MMF) 750 mg<br/>q12 hour and prednisolone at 5 mg daily at Nasser Institute, Cairo, Egypt from<br/>January to September 2016. Patients were randomized into the esomeprazole<br/>group (25) or pantoprazole group (22) receiving the same dose (40 mg once daily).<br/>The study outcomes included clinical signs of rejection and renal function<br/>decline, assessed by elevations in serum creatinine, caused by cyclosporine level<br/>variations in either of the two study groups. Renal function, C0 and CBC measurements were measured at baseline and monthly for 6 months. The mean C0<br/>values were higher in the pantoprazole group than in the esomeprazole group in<br/>the sixth month only (P = .007). Serum creatinine level was lower in the sixth<br/>month than at baseline in the esomeprazole group (P = .004). There were no<br/>signs of rejection biochemical or clinical in any of the study groups. In conclusion,<br/>PPIs should be used with caution and doses should be titrated to reach the C0 targets in RTR, which is of more importance in pantoprazole than esomeprazole to<br/>avoid C0 level elevation or decline affecting the allograft function |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
Text in English, abstracts in English and Arabic. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Clinical Pharmacy |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Materials specified |
DSpace electronic resource |
| Uniform Resource Identifier |
<a href="http://repository.fue.edu.eg/xmlui/handle/123456789/5773">http://repository.fue.edu.eg/xmlui/handle/123456789/5773</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Thesis |
| Source of classification or shelving scheme |
Dewey Decimal Classification |