MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03462ntm a2200325 i 4500 |
| 001 - CONTROL NUMBER |
|---|
| control field |
12102116 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20211110105737.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
150118s2021 ua a f bm 000 0 eng | |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
EG-EULC |
| Transcribing agency |
EG-EULC |
| Description conventions |
rda |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| Language code of summary or abstract/overprinted title or subtitle |
ara |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
615.321 |
| Item number |
E.Y.C |
| Edition number |
22 |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Elkhawas, Yasmin Alaa Eldin Ahmed, |
| 9 (RLIN) |
33894 |
| Relator term |
author. |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Chemical and biological evaluation of bioactive secondary metabolites from endophytic fungi Isolated from marine organisms / |
| Statement of responsibility, etc |
By Yasmin Alaa Eldin Ahmed Elkhawas, assistant lecturer Pharmacognosy, Faculty of Pharmacy, Future University in Egypt. |
| 246 15 - VARYING FORM OF TITLE |
|---|
| Title proper/short title |
التقييم الكميائي والحيوى لمركبات الأيض الثانوية النشطة حيويا من الفطريات المتكافلة المفصولة من الكائنات البحرية |
| 264 #1 - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Date of publication, distribution, etc |
2021 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
140 pages, 3 pages : |
| Other physical details |
illustrations (black and white) ; |
| Dimensions |
24 cm |
| 336 ## - CONTENT TYPE |
|---|
| Source |
rdacontent |
| Content type term |
text |
| 337 ## - MEDIA TYPE |
|---|
| Source |
rdamedia |
| Media type term |
unmediated |
| 338 ## - CARRIER TYPE |
|---|
| Source |
rdacarrier |
| Carrier type term |
volume |
| 500 ## - GENERAL NOTE |
|---|
| General note |
Under the Supervision of Prof. Dr. Abdel Nasser B. Singab, Professor of Pharmacognosy, Head of Drug Discovery Research and Development Center- Faculty of Pharmacy- Ain Shams University, Prof. Dr. Osama M. Salama, Professor of Pharmacognosy, Former Vice President- Future University in Egypt, Associate Prof. Dr. Eman K. Alsayed, Associate Professor of Pharmacognosy, Faculty of Pharmacy - Ain Shams University, Associate Prof. Dr. Nada M. Mostafa, Associate Professor of Pharmacognosy, Faculty of Pharmacy - Ain Shams University, Dr. Mokhtar M. Bishr ,Technical Director, Plant Manager of Arab Co. For Pharmaceuticals & Medicinal Plants (Mepaco)<br/><br/><br/><br/> |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Thesis (Ph.D.)-Ain Shams university, Faculty of pharmacy, Department of Pharmacognosy, 2021. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc |
Includes bibliographical references. |
| 520 3# - SUMMARY, ETC. |
|---|
| Summary, etc |
Two marine derived fungi were isolated from Red sea soft coral Sarcophyton ehrenbergi,<br/>namely, Aspergillus flavus and A. nomius. These fungi were cultured using solid rice media.<br/>Chromatographic studies on different extracts, resulted in isolation of 15 compounds. These<br/>compounds were classified according to their chemical nature into six categories: (1) pyrones,<br/>(2) cyclodepsipeptides, (3) diketopiperazines, (4) indoles, (5) benzo-furanones (6) steroids,<br/>using different tools of spectroscopic techniques. Furthermore, these compounds were<br/>confirmed by LC-MS/MS. Regarding the bioactivities of the extracts and the isolated<br/>compounds, two compounds scopularides A & B from A. flavus showed antifungal, anti-H. <br/>pylori and anti -TB activities<br/>. Scopularide A showed potent antifungal, anti-H- pylori activities<br/>while scopularide B revealed potent activity only against Candida albicans and H- pylori. <br/>Moreover, the total extract of A. flavus showed larvicidal activity due to the presence of these<br/>two scopularides. The larvicidal and antimicrobial activities were confirmed by carrying out<br/>in-silico molecular docking against Candida albicans, A. niger, and also against certain<br/>biochemical enzymes to identify the mode of action by which these tested samples exerts their<br/>activity. |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
Text in English, abstracts in English and Arabic. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Pharmacognosy |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Medicinal plants |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Materials specified |
DSpace electronic resource |
| Uniform Resource Identifier |
<a href="http://repository.fue.edu.eg/xmlui/handle/123456789/5866">http://repository.fue.edu.eg/xmlui/handle/123456789/5866</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Thesis |
| Source of classification or shelving scheme |
Dewey Decimal Classification |