MARC details
| 000 -LEADER |
| fixed length control field |
02893nam a22003377i 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
| fixed length control field |
220704s2022 ua a|||f bm|| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
| Original cataloging agency |
EG-NcFUE |
| Transcribing agency |
EG-NcFUE |
| Modifying agency |
EG-NcFUE |
| Description conventions |
rda |
| 041 0# - LANGUAGE CODE |
| Language code of text/sound track or separate title |
eng |
| Language code of summary or abstract/overprinted title or subtitle |
ara |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
| Edition number |
22 |
| Classification number |
616.994061 |
| Item number |
A.M.D |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
| Personal name |
Abdelshaheed, Mennatallah Mahmoud |
| Relator term |
author. |
| 245 10 - TITLE STATEMENT |
| Title |
Design, Synthesis and Biological Evaluation of New Fused Piperidine Analogues as Anticancer Agents / |
| Statement of responsibility, etc |
by Mennatallah Mahmoud Abdelshaheed Bachelor of Pharmacy (Clinical Pharmacy), (2016) Faculty of Pharmacy, Mansoura University ; Supervisors : Prof. Dr. Hussein I. El-Subbagh Professor of Medicinal Chemistry, Faculty of Pharmacy, Mansoura Universit, Prof. Dr. Khairia M. Youssef Professor of Pharmaceutical Chemistry, Faculty of Pharmacy, Future University in Egypt, Dr. Iten M. Fawzy Lecturer of Pharmaceutical Chemistry, Faculty of Pharmacy, Future University in Egypt. |
| 246 35 - VARYING FORM OF TITLE |
| Title proper/short title |
تصميم و تشييد و تقييم بعض مشتقات البيبيريدين الجديدة كمضادات للسرطان |
| 264 #0 - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
| Date of publication, distribution, etc |
2022 |
| 300 ## - PHYSICAL DESCRIPTION |
| Extent |
124 pages : |
| Other physical details |
illustrations ; |
| Dimensions |
24 cm |
| 336 ## - CONTENT TYPE |
| Source |
rdacontent |
| Content type term |
text |
| Content type code |
txt |
| 337 ## - MEDIA TYPE |
| Source |
rdamedia |
| Media type term |
unmediated |
| Media type code |
n |
| 338 ## - CARRIER TYPE |
| Source |
rdacarrier |
| Carrier type term |
volume |
| Carrier type code |
nc |
| 500 ## - GENERAL NOTE |
| General note |
Supervisors : Prof. Dr. Hussein I. El-Subbagh, Professor of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Prof. Dr. Khairia M. Youssef, Professor of Pharmaceutical Chemistry, Faculty of Pharmacy, Future University in Egypt, Dr. Iten M. Fawzy, Lecturer of Pharmaceutical Chemistry, Faculty of Pharmacy, Future University in Egypt. |
| 502 ## - DISSERTATION NOTE |
| Dissertation note |
Thesis (M.Sc.)--Future University in Egypt, Faculty of pharmacy, Medicinal Chemistry, 2022. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
| Bibliography, etc |
Includes bibliographical references (pages 104- 124). |
| 520 3# - SUMMARY, ETC. |
| Summary, etc |
Cancer is a serious health problem and is one of the leading causes of death worldwide. <br/>Piperidine is an essential pharmacophore and a favoured scaffold in the field of drug design. <br/>Piperidine nucleus exhibited great potential in chemotherapy. Previous studies have reported <br/>the antiproliferative effect of piperidine moiety against different cancer cell lines. Piperidine <br/>was found to be able to cause tubulin inhibition and induce apoptosis and cell cycle arrest in <br/>various types of cancer cells. In this thesis four different series of piperidine derivatives <br/>inspired by Curcumin were designed, synthesised, and tested in vivo and in vitro for their <br/>antitumor effect. |
| 546 ## - LANGUAGE NOTE |
| Language note |
Text in English, abstract in English and Arabic. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name as entry element |
Cancer |
| General subdivision |
Treatment. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name as entry element |
Antineoplastic agents. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
| Topical term or geographic name as entry element |
Medicine. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
| 9 (RLIN) |
33951 |
| Personal name |
El-Subbagh, Hussein I. |
| Relator term |
supervisor |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
| 9 (RLIN) |
33952 |
| Personal name |
Youssef, Khairia M. |
| Relator term |
supervisor |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
| 9 (RLIN) |
33953 |
| Personal name |
Fawzy, Iten M. |
| Relator term |
supervisor |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
| Uniform Resource Identifier |
http://repository.fue.edu.eg/xmlui/handle/123456789/6062 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
| Item type |
Thesis |