MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03399cam a22003494i 4500 |
| 001 - CONTROL NUMBER |
|---|
| control field |
4994692 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20200915105538.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
990304s1999 gw a b 001 0 eng |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
3540646000 (wireobind : alk. paper) |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
DLC |
| Transcribing agency |
DLC |
| Modifying agency |
DLC |
| Description conventions |
rda |
| 082 00 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
612.670724 |
| Edition number |
21 |
| Item number |
S |
| 245 00 - TITLE STATEMENT |
|---|
| Title |
Studies of aging / |
| Statement of responsibility, etc |
Hal Sternberg, Paola S. Timiras (eds.). |
| 264 #1 - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc |
Berlin ; |
| -- |
New York : |
| Name of publisher, distributor, etc |
Springer, |
| Date of publication, distribution, etc |
[1999] |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
xi, 208 pages : |
| Other physical details |
illustrations ; |
| Dimensions |
24 cm |
| 336 ## - CONTENT TYPE |
|---|
| Source |
rdacontent |
| Content type term |
text |
| 337 ## - MEDIA TYPE |
|---|
| Source |
rdamedia |
| Media type term |
unmediated |
| 338 ## - CARRIER TYPE |
|---|
| Source |
rdacarrier |
| Carrier type term |
volume |
| 490 0# - SERIES STATEMENT |
|---|
| Series statement |
Springer lab manual |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc |
Includes bibliographical references and index. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
A Molecular Methods: Introduction to Molecular Methods --<br/>1 Genotypic Selection of Age-Related DNA Rearrangements by PCR --<br/>2 Measurement of Antioxidants in Cutaneous Tissues --<br/>B Cellular Methods: Introduction to Cellular Methods --<br/>3 Cellular Aging / Replicative Senescence --<br/>4 Methods for Evaluating a Slice Culture Model of Alzheimer's Disease --<br/>5 Cell Death --<br/>6 Method for Studying the Migration of Aging Vascular Smooth Muscle Cells --<br/>7 Sensitized Chemiluminescence and Fluorescence Methods in Studies of Oxidative Stress --<br/>C Animal Models: Introduction to Animal Models --<br/>8 How to Choose An Animal Model --<br/>9 Measuring Mortality and Reproduction in Large Cohorts of the Mediterranean Fruit Fly --<br/>D Physiological Methods: Introduction to Physiological Methods --<br/>10 Methods for Evaluating in Vivo Rodent Models for Alzheimer's Disease --<br/>11 Dietary Restriction in Aging --<br/>12 Methods for the Evaluation of the Hypothalamo-Pituitary-Adrenoccortical Axis in the Aged Rat --<br/>13 Assessing Blood Replacement Fluids for Organ Preservation and Low Temperature Surgery --<br/>14 Brain Imaging in Normal and in Alzheimer's Disease. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
Interest in the study of the biology of aging especially as it relates to humans has increased steadily in the last 50 years and continues today to be at the forefront of experimental biology. Due to the many recent advances in this area selection of the best experimental approach may be difficult. It is the purpose of this laboratory manual to provide the researcher with a specific group of techniques with emphasis on hands-on information. A variety of protocols using molecular, cellular and physiological techniques are presented in detail and appropriate animal models have been selected for the study of aging and aging-related diseases. Non-invasive in vivo techniques are described for the study of Alzheimer's dementia and cardiovascular diseases. Techniques for detection of oxidative processes are presented to explore the role of free radicals in causing cell damage and mutations as well as techniques to study apoptosis for its role in cell aging. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Aging |
| General subdivision |
Research |
| -- |
Methodology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Older people |
| General subdivision |
Diseases |
| -- |
Research |
| -- |
Methodology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Geriatrics |
| General subdivision |
Methodology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Sternberg, Hal, |
| Dates associated with a name |
1953-, |
| 9 (RLIN) |
8168 |
| Relator term |
editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Timiras, Paola S., |
| Dates associated with a name |
1923-, |
| 9 (RLIN) |
8169 |
| Relator term |
editor. |
| 906 ## - LOCAL DATA ELEMENT F, LDF (RLIN) |
|---|
| a |
7 |
| b |
cbc |
| c |
orignew |
| d |
1 |
| e |
ocip |
| f |
19 |
| g |
y-gencatlg |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Books |