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Pharmacokinetics for the pharmaceutical scientist / John G. Wagner.

By: Material type: TextTextPublisher: Boca Raton: CRC Press, 2018Description: xvii, 316 pages : illustration ; 24 cmContent type:
  • text
Media type:
  • unmediated
Carrier type:
  • volume
ISBN:
  • 9780367402402
Subject(s): DDC classification:
  • 615.7 22 W.J.P
Online resources:
Contents:
Cover; Half Title; Title Page; Copyright Page; Contents; Introduction; Chapter 1. Simple Linear Models; Model I. One-Compartment Open Model with Bolus Intravenous Administration; Model II. One-Compartment Open Model with First-Order Absorption; Model III. One-Compartment Open Model with Zero-Order Input; Model IV. One-Compartment Open Model with Bolus Intravenous Injection and Intravenous Infusion; Model V. One-Compartment Open Model with Two Parallel First-Order Input Sites; Model VI. One-Compartment Open Model with Two Consecutive First-Order Input Rate Constants Model VII. One-Compartment Open Model with Parallel First- and Zero-Order InputsChapter 2. More Complicated Linear Models; Model VIII. The Classical Two-Compartment Open Model with Central Compartment Elimination and Bolus Intravenous Administration; Model IX. The Rowland Two-Compartment Open Model with Peripheral Elimination and Bolus Intravenous Injection; Model X. The Classical Two-Compartment Open Model with First-Order Absorption; Model XI. The Rowland Two-Compartment Open Model with Peripheral Absorption and Elimination Model XII. The Classical Two-Compartment Open Model with Central Compartment Elimination and Zero-Order InputModel XIII. The Classical Two-Compartment Open Model with Two Parallel First-Order Inputs; Model XIV. The Classical Two-Compartment Open Model with Sequential First-Order Inputs; Model XV. The Classical Two-Compartment Open Model with Parallel Zero-Order and First-Order Inputs; Model XVI. Classical Two-Compartment Open Model with Bolus Loading Dose and Zero-Order Input; Model XVII. Classical Two-Compartment Open Model with Two Consecutive Zero-Order Infusion Rates Chapter 3. Complicated Linear ModelsModel XVIII. Family of Reversible Metabolism Models; Model XIX. Three-Compartment Open Model with Central Compartment Elimination and Bolus Intravenous Administration; Model XX. Three-Compartment Open Model with Central Compartment Elimination and First-Order Absorption; Model XXI. Three-Compartment Open Model with Central Compartment Elimination and Two Consecutive First-Order Inputs; Model XXII. Three-Compartment Open Model with Central Compartment Elimination and Zero-Order Input Model XXIII. First-Pass Three-Compartment Open Model with Bolus Intravenous AdministrationModel XXIV. First-Pass Three-Compartment Open Model with First-Order Absorption; Model XXV First-Pass Three-Compartment Open Model with Constant Rate Infusion; Chapter 4. Linear Multicompartment Disposition Parameters from Downslope Extravascular C, t Data; Intrasubject Variation of Disposition; Methods of Estimating Disposition Parameters When Disposition Is Biexponential; Methods of Estimating Disposition Parameters When Disposition Is Triexponential; Chapter 5. Noncompartmental and System Analysis
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Includes bibliographical references (pages 305-312) and index.

Cover; Half Title; Title Page; Copyright Page; Contents; Introduction; Chapter 1. Simple Linear Models; Model I. One-Compartment Open Model with Bolus Intravenous Administration; Model II. One-Compartment Open Model with First-Order Absorption; Model III. One-Compartment Open Model with Zero-Order Input; Model IV. One-Compartment Open Model with Bolus Intravenous Injection and Intravenous Infusion; Model V. One-Compartment Open Model with Two Parallel First-Order Input Sites; Model VI. One-Compartment Open Model with Two Consecutive First-Order Input Rate Constants
Model VII. One-Compartment Open Model with Parallel First- and Zero-Order InputsChapter 2. More Complicated Linear Models; Model VIII. The Classical Two-Compartment Open Model with Central Compartment Elimination and Bolus Intravenous Administration; Model IX. The Rowland Two-Compartment Open Model with Peripheral Elimination and Bolus Intravenous Injection; Model X. The Classical Two-Compartment Open Model with First-Order Absorption; Model XI. The Rowland Two-Compartment Open Model with Peripheral Absorption and Elimination
Model XII. The Classical Two-Compartment Open Model with Central Compartment Elimination and Zero-Order InputModel XIII. The Classical Two-Compartment Open Model with Two Parallel First-Order Inputs; Model XIV. The Classical Two-Compartment Open Model with Sequential First-Order Inputs; Model XV. The Classical Two-Compartment Open Model with Parallel Zero-Order and First-Order Inputs; Model XVI. Classical Two-Compartment Open Model with Bolus Loading Dose and Zero-Order Input; Model XVII. Classical Two-Compartment Open Model with Two Consecutive Zero-Order Infusion Rates
Chapter 3. Complicated Linear ModelsModel XVIII. Family of Reversible Metabolism Models; Model XIX. Three-Compartment Open Model with Central Compartment Elimination and Bolus Intravenous Administration; Model XX. Three-Compartment Open Model with Central Compartment Elimination and First-Order Absorption; Model XXI. Three-Compartment Open Model with Central Compartment Elimination and Two Consecutive First-Order Inputs; Model XXII. Three-Compartment Open Model with Central Compartment Elimination and Zero-Order Input
Model XXIII. First-Pass Three-Compartment Open Model with Bolus Intravenous AdministrationModel XXIV. First-Pass Three-Compartment Open Model with First-Order Absorption; Model XXV First-Pass Three-Compartment Open Model with Constant Rate Infusion; Chapter 4. Linear Multicompartment Disposition Parameters from Downslope Extravascular C, t Data; Intrasubject Variation of Disposition; Methods of Estimating Disposition Parameters When Disposition Is Biexponential; Methods of Estimating Disposition Parameters When Disposition Is Triexponential; Chapter 5. Noncompartmental and System Analysis

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