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DNA, words and models / Stéphane Robin, François Rodolphe, Sophie Schbath.

By: Contributor(s): Material type: TextTextLanguage: English Original language: French Publisher: Cambridge, UK ; New York : Cambridge University Press, 2005Description: xx, 138 pages : illustrations ; 24 cmContent type:
  • text
Media type:
  • unmediated
Carrier type:
  • volume
ISBN:
  • 052184729X (hbk.)
Uniform titles:
  • ADN, mots, et modéles. English
Subject(s): DDC classification:
  • 572.8633 22 R.S.D
Online resources:
Contents:
Introduction. The context -- Randomness and models -- A bit of biology -- Simple models for biological sequences. Why a model? -- Permutation model -- Bernoulli model -- Introduction to Markov chain models. Assumptions -- Markov chain order 1 -- Markov chain order m -- Estimation of the parameters -- Taking heterogeneities into account. Phased chains -- Piecewise homogeneous Markov chains -- Translation conditional models -- Statistical properties of word occurrences. Count -- Positions and distances -- Distribution along the sequence -- Words with unexpected frequencies. Exact distribution and approximations -- Influence of the model -- Over-representations of Chi sites in E. coli and H. influenzae -- Under-representation of palindromes of length 6 in E. coli and in the phage Lambda -- Words with unexpected locations. Chi sites in the genome of H. influenzae -- Distribution of palindromes in E. coli's genome -- Detection of promoter sites in B. subtilis -- The last word.
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Item type Current library Call number Status Date due Barcode
Books Books Main library A9 572.8633 R.S.D (Browse shelf(Opens below)) Available 00002487

Includes bibliographical references (pages 134-136) and index.

Introduction. The context -- Randomness and models -- A bit of biology -- Simple models for biological sequences. Why a model? -- Permutation model -- Bernoulli model -- Introduction to Markov chain models. Assumptions -- Markov chain order 1 -- Markov chain order m -- Estimation of the parameters -- Taking heterogeneities into account. Phased chains -- Piecewise homogeneous Markov chains -- Translation conditional models -- Statistical properties of word occurrences. Count -- Positions and distances -- Distribution along the sequence -- Words with unexpected frequencies. Exact distribution and approximations -- Influence of the model -- Over-representations of Chi sites in E. coli and H. influenzae -- Under-representation of palindromes of length 6 in E. coli and in the phage Lambda -- Words with unexpected locations. Chi sites in the genome of H. influenzae -- Distribution of palindromes in E. coli's genome -- Detection of promoter sites in B. subtilis -- The last word.

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