Biopharmaceutics and pharmacokinetics / Jayant S. Kulkarni, A.P. Pawar, V.P. Shedbalkar.

Includes index.

Absorption of drugs -- distribution of drugs -- drug metabolism (bio-transformation) -- excretion -- prodrugs -- pharmaceutics - basic considerations -- one compartment mode -- multi-compartment model -- nonlinear pharmaceutics -- non- compartmental analysis -- applications pharmaceutics -- bio-equivalence -- introduction to bioanalysis

Biopharmaceutics and Pharmacokinetics deals with what body does to the drug. In this book, along with the fundamentals of absorption, distribution, metabolism and excretion, current topics such as in vitro systems have also been introduced. In case of pharmacokinetics models, authors have tried to keep mathematical part simpler and minimal. This book also introduces "non compartmental models", which are gaining increasing importance in the analysis of pharmacokinetic data. In the chapter "applications of pharamacokinetics", newer concepts such as chronopharmacokinetics have been introduced. Bioequivalence is covered in last two chapters. Besides clinical aspects of bioequivalence, some of the important aspects of bioanalysis have also been introduced. The regulatory aspect of bioequivalence has also been covered. Thus an attempt has been made to cover all the basic aspects of biopharmaceutics and pharmacokinetics in a reader-friendly manner