Nanotechnology for the delivery of therapeutic nucleic acids / edited by Dan Peer.

Contributor(s):

Peer, Dan, 1972- [editor.]

Material type: Text

TextSeries: Pan stanford series on biomedical nanotechnologyPublisher: Singapore : Pan Stanford Publishing, 2013Distributor: London : Taylor & Francis, 2013Description: xiii, 226 pages ; 23 cmContent type:

text

Media type:

unmediated

Carrier type:

volume

ISBN:

9814411043 (hardcover)
9789814411042 (hardcover)

Subject(s):

DDC classification:

23 615.6 N

Online resources:

Contents:

Lipoplexes and polyplexes : from gene delivery to gene expression / Gerardo Byk, Mirit Cohen-Ohana, and Fiana Mirkin -- 2. Cationic polymers for the delivery of therapeutic nucleotides / Wahid Khan, Saravanan Muthupandian, and Abraham J. Domb -- 3. Membrane/core nanoparticles for delivery of therapeutic nucleic acid / Younjee Chung and Leaf Huang -- 4. Delivery of single siRNA molecules / Caroline Palm-Apergi and Steven F. Dowdy -- 5. Cell-specific aptamer-functionalized RNAi : a new prospect for targeted siRNA delivery / Jiehua Zhou and John J. Rossi -- 6. Bioresponsive nanoparticles for the intracellular delivery of RNAi therapeutics / Kenneth Alan Howard -- 7. Lipid-like delivery materials for efficient siRNA delivery / James Dahlman, Robert Langer, and Michael Goldberg -- 8. Manipulation of leukocytes using therapeutic RNAi delivered by targeted and stabilized nanoparticles / Dan Peer -- 9. Lowering the siRNA delivery barrier : alginate scaffolds and immune stimulation / Jana McCaskill, Sherry Wu, Norliana Khairuddin, and Nigel A.J. McMillan.

Summary: Nucleic acid (NA) therapeutics has been extensively studied both in the academia and in the pharmaceutical industry and is still considered the promise for new therapeutic modalities, especially in personalized medicine. The only hurdle that limits the translation of NA therapeutics from an academic idea to the new therapeutic modality is the lack of efficient and safe delivery strategies. Nanotechnology for the Delivery of Therapeutic Nucleic Acids , written by world experts in the field of nanotechnology for NA delivery, the contributing authors bring together the state of the art in delivery strategies with strong emphasis on aspects that are of essence to the pharmaceutical industry, such as stability, general toxicity, immune-toxicity, pharmacokinetics, efficacy, and validation of new drug targets using unique approaches based on exquisite nanotechnology strategies.

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Holdings
Item type	Current library	Collection	Call number	Status	Date due	Barcode
Books	Main library A11	Pharmacy ( Pharmaceutical Technology )	615.6 N (Browse shelf(Opens below))	Available		00011526

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Nucleic acid (NA) therapeutics has been extensively studied both in the academia and in the pharmaceutical industry and is still considered the promise for new therapeutic modalities, especially in personalized medicine. The only hurdle that limits the translation of NA therapeutics from an academic idea to the new therapeutic modality is the lack of efficient and safe delivery strategies. Nanotechnology for the Delivery of Therapeutic Nucleic Acids , written by world experts in the field of nanotechnology for NA delivery, the contributing authors bring together the state of the art in delivery strategies with strong emphasis on aspects that are of essence to the pharmaceutical industry, such as stability, general toxicity, immune-toxicity, pharmacokinetics, efficacy, and validation of new drug targets using unique approaches based on exquisite nanotechnology strategies.

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