Using mass spectrometry for drug metabolism studies - Korfmacher, Walter A. (Boca Raton, FL : CRC Press, 2005)
Bioanalytical Assays in a Drug Discovery Environment -- Walter A. Korfmacher Drug Metabolism In-vitro and In-vivo Results: How do these Data Support Drug Discovery? -- Thomas N. Thompson High Throughput Strategies forIn Vitro ADME Assays: How Fast Can We Go? --Dan Kassel, Matrix Effects: Causes and Solutions -- Hong Mei Direct Plasma Analysis Systems -- Yunsheng Hsieh Acyl Glucuronides-Assays and Issues -- Sam Wainhaus Utilizing Higher Mass Resolution in Quantitative Assays -- Xiaoying Xu Special Requirements for Metabolite Characterization -- Kathleen Cox APPI: A New Ionization Source for LC-MS/MS Assays -- Yunsheng Hsieh Q Trap MS: a New Tool for Metabolite Identification -- Gerard Hopfgartner and Manfred Zell MS Imaging: New Technology Provides New Opportunities -- Michelle L. Reyzer and Richard M. Caprioli Understanding the Role and Potential of Infusion Nanoelectrospray Ionization for Pharmaceutical Bioanalysis -- Bradley L. Ackermann and Jean-Marie Dethy
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Includes bibliographical references and index.
Keywords: Drugs -- Metabolism; Drugs -- Spectra; Mass spectrometry; Pharmaceutical Preparations -- metabolism; Drug Design; Drug Evaluation, Preclinical -- methods; Spectrum Analysis, Mass -- methods