TY - BOOK AU - Lieberman,Michael AU - Peet,Alisa AU - Lieberman,Michael TI - Marks' essentials of medical biochemistry: a clinical approach SN - 9781451190069 (pbk.) AV - QP514.2 .L54 2015 U1 - 612.015 23 PY - 2015///] CY - Philadelphia PB - Wolters Kluwer KW - Biochemical Phenomena KW - Clinical Medicine KW - Metabolism N1 - Includes indexes; dental bookfair2016; Preceded by: Marks' essential medical biochemistry / Michael Lieberman, Allan Marks, Colleen Smith. c2007; Based on: Marks' basic medical biochemistry / Michael Lieberman, Allan Marks, Alisa Peet. 4th ed. c2013; An overview of fuel metabolism -- Water, acids, bases, and buffers -- Structures of the major compounds of the body -- Amino acids in proteins -- Structure-function relationships in proteins -- Enzymes as catalysts -- Regulation of enzymes -- Cell structure and signaling by chemical messengers -- Structure of the nucleic acids -- Synthesis of DNA -- Transcription: synthesis of RNA -- Translation: synthesis of proteins -- Regulation of gene expression -- Use of recombinant DNA techniques in medicine -- Cellular bioenergetics: ATP and O2 -- Tricarboxylic acid cycle -- Oxidative phosphorylation, mitochondrial function, and oxygen radicals -- Generation of ATP from glucose: glycolysis -- Oxidation of fatty acids and ketone bodies -- Basic concepts in the regulation of fuel metabolism by insulin, glucagon, and other hormones -- Digestion, absorption, and transport of carbohydrates -- Formation and degradation of glycogen. Pathways of sugar metabolism: fructose, galactose, pentose phosphate pathway, and ethanol metabolism -- Synthesis of glycosides, lactose, glycoproteins, and glycolipids and proteoglycans -- Gluconeogenesis and maintenance of blood glucose levels -- Digestion and transport of dietary lipids -- Synthesis of fatty acids, triacylglycerols, eicosanoids, and the major membrane lipids -- Cholesterol absorption, synthesis, metabolism and fate -- Integration of carbohydrate and lipid metabolism -- Protein digestion and amino acid absorption -- Fate of amino acid nitrogen: urea cycle -- Synthesis and degradation of amino acids and amino acid derived products -- Tetrahydrofolate, vitamin B12, and S-adenosylmethionine -- Purine and pyrimidine metabolism -- Intertissue relationships in the metabolism of amino acids N2 - Marks’ Essentials of Medical Biochemistry takes a patient-oriented approach that links biochemistry to physiology and pathophysiology, allowing students to apply fundamental concepts to the practice of medicine. Based on the established text, Marks’ Basic Medical Biochemistry, Marks’ Essentials is streamlined to focus only on the most essential biochemical concepts, while maintaining intuitively organized chapters centered on hypothetical patient vignettes and helpful icons for smooth navigation. • Full-color illustrations of chemical structures and biochemical pathways elucidate core concepts and enhance understanding of the text • Hypothetical patient vignettes ensure clinical relevance and help connect biochemistry to human health and disease • Helpful icons guide you through each chapter and identify key concepts such as signs and symptoms, clinical pearls, treatment options and outcomes, and more • Chapter Outlines and Key Points allow readers to preview and review chapter content • End-of-Chapter Review Questions and Summary Disease Tables highlight the take-home messages and reinforce knowledge UR - http://repository.fue.edu.eg/xmlui/handle/123456789/1845 ER -