TY  - BOOK
AU  - Roche,Victoria F.
AU  - Zito,S.William
AU  - Lemke,Thomas L.
AU  - Williams,David A.
TI  - Foye's principles of medicinal chemistry
SN  - 9781496385024
AV  - RS403 .P75 2020
U1  - 616.0756 23
PY  - 2020///]
CY  - Philadelphia
PB  - Wolters Kluwer
KW  - Pharmaceutical chemistry
KW  - Chemistry, Pharmaceutical
N1  - Includes bibliographical references and indexes; Part I  Principles
CHAPTER 1  Introduction to Medicinal Chemistry
CHAPTER 2  Foundational Principles and Functional Group Impact on Activity
CHAPTER 3  Drug Metabolism
CHAPTER 4  Membrane Drug Transporters
CHAPTER 5  Principles of Biotechnology-Derived Drugs
Part II  Receptor Targets
CHAPTER 6  G Protein–Coupled Receptors
CHAPTER 7  Nuclear Receptors
CHAPTER 8  Ion Channel Receptors
CHAPTER 9  Enzyme/Catalytic Receptors
Part III  Pharmacodynamic Agents
Section 1 Drugs Impacting the Central Nervous System
CHAPTER 10  Drugs Used to Treat Neuromuscular Disorders
CHAPTER 11  Drugs Used to Treat Mental, Behavioral, and Cognitive Disorders
CHAPTER 12  Drugs Used to Induce/Support Sedation or Anesthesia
CHAPTER 13  Drugs Used to Treat Seizure Disorders
Section 2 Drugs Impacting Pain Perception
CHAPTER 14  Drugs Used to Treat Pain: Centrally Acting Agents
CHAPTER 15  Drugs Used to Treat Pain: Peripherally Acting Agents
Section 3 Drugs Impacting the Cardiovascular System
CHAPTER 16  Drugs Used to Treat Cardiac Disorders
CHAPTER 17  Drugs Used to Treat Hypertensive/Hypotensive Disorders
CHAPTER 18  Drugs Used to Treat Coagulation Disorders
CHAPTER 19  Drugs Used to Treat Dyslipidemic Disorders
Section 4 Drugs Impacting Hormonal Systems
CHAPTER 20  Drugs Used to Treat Diabetic Disorders
CHAPTER 21  Drugs Used to Treat Inflammatory and Corticosteroid Deficiency Disorders
CHAPTER 22  Drugs Used to Treat Thyroid Disorders
CHAPTER 23  Drugs Used to Treat Calcium-Dependent Disorders
CHAPTER 24  Drugs Used to Advance Men’s and Women’s Health
Section 5 Drugs Impacting Immune, Gastrointestinal and Genitourinary Systems
CHAPTER 25  Drugs Used to Treat Allergic Disorders
CHAPTER 26  Drugs Used to Treat Gastrointestinal and Genitourinary Disorders
Section 6 Drugs Impacting Ocular, Nasal and Pulmonary Systems
CHAPTER 27  Drugs Used to Treat Ocular and Nasal Congestion Disorders
CHAPTER 28  Drugs Used to Treat Pulmonary Disorders
Section 7 Drugs Impacting Infectious and Neoplastic Disease Processes
CHAPTER 29  Drugs Used to Treat Bacterial Infections
CHAPTER 30  Drugs Used to Treat Viral Infections
CHAPTER 31  Drugs Used to Treat Fungal Infections
CHAPTER 32  Drugs Used to Treat Parasitic Infections
CHAPTER 33  Drugs Used to Treat Neoplastic Diseases
Section 8 Therapeutic Biologics
CHAPTER 34  Biologics Used in the Treatment of Disease
Part IV  Disease State Management
CHAPTER 35  Coronary Artery Disease
CHAPTER 36  Rheumatoid Arthritis
CHAPTER 37  Nutrition and Obesity
Appendix A  cLogP and cLogDpH 7.4 Values of Selected Drugs
Appendix B  Predicted pKa Values of Commonly Prescribed Drugs
Appendix C  pH Values of Biological Fluids
Subject Index
Drug Index
N2  - "With expert contributions from experienced educators, research scientists and clinicians, Foye's Principles of Medicinal Chemistry, Eighth Edition is an invaluable resource for professional students, graduate students and pharmacy faculty alike . This 'gold standard' text explains the chemical basis of drug action, emphasizing the structure-activity relationships, physicochemical-pharmacokinetic properties, and metabolic profiles of the most commonly used drugs"--
ER  -