Microcapsules and nanoparticles in medicine and pharmacy - Donbrow, Max (Boca Raton : CRC Press, 1992)
Introduction and Overview -- PART I: ADVANCES IN PRODUCTION TECHNOLOGY AND CHARACTERIZATION OF MICROCAPSULES, MICROSPHERES, AND NANOPARTICLES -- Developments in Phase Separation Methods, Aggregation Control, and Mechanisms of Microencapsulation (Max Donbrow) -- Formation of Degradable Drug-Loaded Microparticles by In-Liquid Drying Processes (Curt Thies) -- Fluid-Bed Spray Coating (K. Lehmann) -- Polyanhydride Microspheres as Drug Delivery Systems (Edith Mathiowitz and Robert Langer) -- Nanoparticles - Preparation and Applications (J. Kreuter) -- Recent Advances Using Microencapsulation for Taste Masking of Bitter Drugs (J.A. Bakan, T.C. Powell, R.W. Roark, and P.S. Szotak) -- PART II: BIOLOGICAL TRANSIT AND INTERACTIONS, RELEASE KINETICS, PHARMACOKINETICS AND BIOAVAILABILITY -- Gastrointestinal Transit of Microcapsules (John T. Fell) -- Interaction of Microcapsules with Blood Components (Tamotsu Kondo) -- Recent Advances in Microencapsulation of Drugs to Obtain Reduced Gastric Irritation (J.A. Bakan, T.C. Powell, R.W. Roark, and P.S. Szotak) -- In Vitro Release from Microcapsules and Microspheres (Ivan Jalsenjak) -- The Relation of Release Profiles from Ensembles to Those of Individual Microcapsules and the Influence of Types of Batch Heterogeneity on Release Kinetics (Max Donbrow) -- Pharmacokinetic Considerations Related to Bioavailability of Sustained-Release Microencapsulated Drugs for Oral Use - Assessment of Absorption Rates (Shigeru Goto and Takahiro Uchida) -- PART III: CLINICAL APPLICATIONS, TARGETING, AND LIVING AND ARTIFICIAL ENCAPSULATED CELLS -- Clinical Uses of Microcapsules and Microspheres (Kazuhiko Juni and Masahiro Nakano) -- Chemo-Embolization and Passive Targeting with Degradable Starch Microspheres (Peter Edman and Ingvar Sjoeholm) -- Active Targeting of Microcapsules and Microspheres to Specific Regions (Julia J. Wright and Lisbeth Illum) -- Erythrocytes as Microvesicles (David A. Lewis and H. Oya Alpar) -- Microencapsulation of Living Cells and Tissues -- (Anthony M. Sun, Ivan Vacek, and Isaballa Tai) -- Recent Advances in Artificial Cells with Emphasis on Biotechnological Approaches Based on Microencapsulation (Thomas Ming Swi Chang).
Includes bibliographical references and index
Keywords: Microencapsulation; Biopharmaceutics; Capsules; Drug Carriers; Technology, Pharmaceutical