TY  - BOOK
AU  - Williams,Kevin L
AU  - Weary,Marlys
AU  - Jorgensen,James H
TI  - Endotoxins: pyrogens, LAL testing, and depyrogenation 
SN  - 0824793625
AV  - QP632.E4 P43 2001
U1  - 616.01 23
PY  - 2001///]
CY  - New York
PB  - Marcel Dekker
KW  - Endotoxins
KW  - Analysis
KW  - Pyrogens
KW  - Limulus test
KW  - Drugs
KW  - Microbiology
KW  - analysis
KW  - Infusions, Parenteral
KW  - standards
KW  - Limulus Test
N1  - 1st ed. was published as Pyrogens: endotoxins and LAL testing and depyrogenation, by F. C. Pearson; Includes bibliographical references and index; Historical foundations of pyrogen research; pyrogen, endotoxin, and fever - an overview; endotoxin structure, function, activity; the host response to endotoxin; non-endotoxin microbial pyrogens (lesser endotoxins and superantigens); non-microbial exogenous pyrogens and drug fever; pharmaceutical manufacturing contamination control; endotoxin as a standard; the rabbit pyrogen test; LAL discovery, mechanism, and application; LAL assay development, validation and regulation

N2  - This study describes the environmental presence, detection, properties and biological structure and function of endotoxins in parenteral manufacturing. It includes chapters on asay development, automation, depyrogenation, and regulation of testing by LAL methods
ER  -