TY  - BOOK
AU  - Levacher,Eric
AU  - Blondeau,Jean-Luc
AU  - Bogaerts,Yves
AU  - Picard,Frederique Bordes
AU  - Brosseau,Eloi
AU  - Cocheteux,Bruno
AU  - Kuntz,Thersia
TI  - Capsules : Fields of Application & Industrial Technologies / 
SN  - 9791095285014
U1  - 615.19005 23
PY  - 2016///]
CY  - [Farance]
PB  - Group IMT
KW  - Pharmaceutical technology
KW  - Pharmaceutical industry
N1  - Part 1 – Capsule Manufacture
1. INTRODUCTION
1.1. Definition
1.2. Capsule appearance
1.3. Composition
2. SPECIFICATIONS
2.1. Dimensions, capacities
2.2. Moisture content
2.3 Disintegration time
3. CAPSULE MANUFACTURE
3.1. Manufacturing process
3.2 Manufacturing inspections
Part 2 – Fields of application
1. CAPSULE FILLING PRODUCTS
2. CAPSULES FOR SPECIFIC APPLICATIONS
2.1. Modified release
2.2. Capsules for pulmonary or nasal dispensation systems
2.3. Liquid formulations in capsules
2.4. Other technologies
3. FACING UP TO CURRENT CHALLENGES
3.1. Patient centric design
3.2. Quality by design and industrial efficiency
Part 3 – Industrial implementation
1. CAPSULE FILLING CYCLE
1.1. Orientation and opening
1.2. Filling
1.3. Closing full capsules
1.4. Ejection
2. ALTERNATING MACHINES
2.1. General work flow
3. CONTINUOUS MACHINES
3.1. Single turret principle
3.2. Multiple turret principle
4. DOSING TECHNIQUES
4.1. Powder dosing
4.2. Micropellet filling
4.3. Solid unit form filling
4.4. Micotablet filling
4.5. Liquid and semi-solid filling
5. CONTROL SYSTEMS
5.1. Individual control of powder dosing with strain gauges
5.2. Individual control of pellet dosing
5.3. Individual camera control of microtablet dosing
5.4. Actual weight inspection systems
6. INSTALLATION / CONFIGURATION OF THE CAPSULE FILLING MACHINE
6.1. Standard
6.2. Through the wall 6.3. Modular systems
7. SORTING SYSTEMS / MACHINE EXIT INSPECTION
7.1. Elimination of deformed capsules
7.2. Elimination of empty or part-filled capsules
7.3. Metal detectors
8. CONTAINMENT
8.1. Containment problem
8.2. High-containment in capsule filling
8.3. Cleaning
9. SUBSEQUENT CAPSULE PROCESSING
9.1. Sealing / wrapping
9.2. Enteric film coating
10. TROUBLESHOOTING
10.1. General
10.2. Faults and diagnosis
ER  -