TY  - BOOK
AU  - Robin,Stéphane
AU  - Rodolphe,François
AU  - Schbath,Sophie
TI  - DNA, words and models
SN  - 052184729X (hbk.)
U1  - 572.8633 22
PY  - 2005///
CY  - Cambridge, UK, New York
PB  - Cambridge University Press
KW  - Genetics
KW  - Mathematical models
KW  - Markov processes
N1  - Includes bibliographical references (pages 134-136) and index; Introduction. The context -- Randomness and models -- A bit of biology -- Simple models for biological sequences. Why a model? -- Permutation model -- Bernoulli model -- Introduction to Markov chain models. Assumptions -- Markov chain order 1 -- Markov chain order m -- Estimation of the parameters -- Taking heterogeneities into account. Phased chains -- Piecewise homogeneous Markov chains -- Translation conditional models -- Statistical properties of word occurrences. Count -- Positions and distances -- Distribution along the sequence -- Words with unexpected frequencies. Exact distribution and approximations -- Influence of the model -- Over-representations of Chi sites in E. coli and H. influenzae -- Under-representation of palindromes of length 6 in E. coli and in the phage Lambda -- Words with unexpected locations. Chi sites in the genome of H. influenzae -- Distribution of palindromes in E. coli's genome -- Detection of promoter sites in B. subtilis -- The last word
UR  - http://www.loc.gov/catdir/enhancements/fy0632/2005047088-d.html
UR  - http://www.loc.gov/catdir/enhancements/fy0632/2005047088-t.html
ER  -