TY - BOOK AU - Gabrielsson,Johan AU - Hjorth,Stephan TI - Quantitative pharmacology : : an introduction to integrative pharmacokinetic-pharmacodynamic analysis / SN - 9781466560314 U1 - 615.7 22 PY - 2012/// CY - Sweden : PB - Swedish Pharmaceutic KW - Pharmacokinetics N1 - Includes bibliographical references; Ch. 1. Introduction -- What is PK/PD and quantitative pharmacology -- ch. 2. Principles of kinetics from a pharmacodynamic point of view -- ch. 3. Principles of plasma protein binding -- ch. 4. Principles of dose, time and flow dependencies -- ch. 5. Principles of rapid concentration-response equilibria -- ch. 6. Time delays between plasma concentration and response -- ch. 7. Principles of inter-species scaling ER -