TY - BOOK AU - Stevens,Craig W. TI - Methods for the discovery and characterization of G protein-coupled receptors T2 - Neuromethods SN - 9781617791789 (alk. paper) AV - QP552.G16 M48 2011 U1 - 572.696 22 PY - 2011/// CY - New York PB - Humana Press KW - G proteins KW - Receptors KW - GTP-Binding Proteins KW - Receptors, G-Protein-Coupled N1 - Includes bibliographical references and index; In silico identification of novel G protein-coupled receptors; Alternative pre-mRNA splicing of G protein-coupled receptors; Detecting polymorphisms in G protein-coupled receptor genes; Regulation of the transcription of G protein-coupled receptor genes; Deciphering the evolution of G protein-coupled receptors in vertebrates; New approach to visualize endogenously expressed G protein-coupled receptors in tissues and living cells; Posttranslational regulation of G protein-coupled receptors; Discovering G protein-coupled receptor motifs mediating export from the endoplasmic reticulum; Identifying G protein-coupled receptor escorts, chaperones, and intracellular tethers regulating receptor density at the cell surface; Novel method for determining the kinetics of G protein-coupled receptor plasma membrane expression; Characterizing the pharmacology of G protein-coupled receptors in transfected cell lines; Novel assay technologies for the discovery of G protein-coupled receptor drugs; Discovering cell type-specific patterns of G protein-coupled receptor phosphorylation; Quantifying allosteric modulation of G protein-coupled receptors; Experimental designs for the study of receptor-receptor interactions; Elucidating agonist-selective mechanisms of G protein-coupled receptor desensitization; Detecting the role of arrestins in G protein-coupled receptor regulation; Characterizing molecular mobility and membrane interactions of G protein-coupled receptors; Using RNA interference to downregulate G protein-coupled receptors; Upregulating G protein-coupled receptors with receptor antagonists UR - http://repository.fue.edu.eg/xmlui/handle/123456789/2752 ER -