Aulton's pharmaceutics : the design and manufacture of medicines - Aulton, Michael E.; Taylor, Kevin, 1961- (Edinburgh : Churchill Livingstone/Elsevier, 2013)
1. Design of dosage forms. PART 1: Scientific principles of dosage form design. 2. Dissolution and solubility. 3. Properties of solutions. 4. Surfaces and interfaces. 5. Disperse systems. 6. Rheology. 7. Kinetics. PART 2: Particle science and powder technology. 8. Solid-state properties. 9. Particle size analysis. 10. Particle size reduction and size separation. 11. Mixing. 12. Powder flow. PART 3: Pharmaceutical microbiology and sterilization. 13. Fundamentals of microbiology. 14. Pharmaceutical applications of microbiological techniques. 15. Action of physical and chemical agents on microorganisms. 16. Principles of sterilization. 17. Sterilization in practice. PART 4: Biopharmaceutical principles of drug delivery. 18. Introduction to biopharmaceutics. 19. Gastrointestinal tract - physiology and drug absorption. 20. Bioavailability - physicochemical and dosage form factors. 21. Assessment of biopharmaceutical properties. 22. Dosage regimens. PART 5: Dosage form design and manufacture. 23. Pharmaceutical preformulation. 24. Solutions. 25. Clarification. 26. Suspensions . 27. Emulsions and Creams. 28. Powders, granules and granulation. 29. Drying. 30. Tablets and compaction. 31. Modified-release oral drug delivery. 32. Coating of tablets and multiparticulates. 33. Hard capsules. 34. Soft capsules. 35 Dissolution testing of solid dosage forms. 36 Parenteral drug delivery. 37. Pulmonary drug delivery. 38. Nasal drug delivery. 39. Topical and transdermal drug delivery. 40. Wound dressings. 41. Ocular drug delivery. 42. Rectal and vaginal drug delivery. 43. Design and administration of medicines for children and the elderly. 44. The formulation and manufacture of plant medicines. 45. Pharmaceutical nanotechnology and nanomedicines. 46. Delivery of biopharmaceuticals. Part 6: PACKAGING AND STABILITY OF PHARMACEUTICAL PRODUCTS. 47. Packaging. 48. Chemical stability in dosage forms. 49. Product stability and stability testing. 50. Microbial contamination, spoilage and preservation of medicines.
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Includes bibliographical references and index.
Keywords: Dosage Forms; Biopharmaceutics -- methods; Drug Compounding -- methods; Drug Design