TY - BOOK AU - Mendelsohn,John AU - Howley,Peter M. AU - Israel,Mark A. AU - Gray,Joe W. AU - Thompson,Craig TI - The molecular basis of cancer SN - 9781455740666 (hardcover : alk. paper) AV - RC268.5 .M632 2015 U1 - 616.994071 23 PY - 2015///] CY - Philadelphia, PA PB - Saunders/Elsevier KW - Neoplasms KW - genetics KW - pathology KW - Molecular Biology KW - methods KW - Molecular Targeted Therapy N1 - Includes bibliographical references and index; Cancer: A Genetic Disorder -- Oncogenes and Signal Transduction -- Tumor Suppressor Genes -- DNA Repair Pathways and Human Cancer -- Epigenetics and Cancer -- Infectious Agents and Cancer -- Environmental Carcinogenesis -- Animal Models: Flies, Fish, and Yeast -- Genetic Mouse Models of Cancer -- Cancer Stem Cells and the Microenvironment -- Regulation of the Cell Cycle -- Cell Growth -- The Metabolism of Cell Growth and Proliferation -- Apoptosis, Necrosis, and Autophagy -- Cellular Senescence -- The Role of the Microenvironment in Tumor Initiation, Progression, and Metastasis -- Tumor Angiogenesis -- Invasion and Metastasis -- Inflammation and Cancer -- Cancer Systems Biology: The Future -- Biomarkers for Assessing Risk of Cancer -- Protein Biomarkers for Detecting Cancer: Molecular Screening -- The Technology of Analyzing Nucleic Acids in Cancer -- Understanding and Usin N2 - The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice UR - http://repository.fue.edu.eg/xmlui/handle/123456789/1772 ER -