TY - BOOK AU - Van den Anker,John N. AU - Coppes,Max J. AU - Koren,Gideon TI - Neonatal and pediatric clinical pharmacology T2 - Pediatric clinics of North America, SN - 9781455749188 (hb) U1 - 615.1083 22 PY - 2012/// CY - Philadelphia, Pa. PB - Saunders KW - Pediatric pharmacology KW - Newborn infants KW - Effect of drugs on KW - Child KW - Infant, Newborn KW - Infant KW - Drug Therapy N1 - "October 2012."; Includes bibliographical references and index; Pediatric pharmacokinetics: human development and drug disposition / Ryan S. Funk, Jacob T. Brown, and Susan M. Abdel-Rahman -- Pediatric pharmacogenomics: a systematic assessment of ontogeny and genetic variation to guide the design of statin studies in children / Jonathan Wagner and J. Steven Leeder -- Metabolomics in the developing human being / Aggeliki Syggelou ... [et al.] -- Emerging biomarkers of intrauterine neonatal and pediatric exposures to xenobiotics / Kaitlyn Delano and Gideon Koren -- New ways to detect adverse drug reactions in pediatrics / Michael Rieder -- Pharmacotherapy of pediatric HIV infection / Natella Rakhmanina and B. Ryan Phelps -- How to optimize the evaluation and use of antibiotics in neonates / Evelyne Jacqz-Aigrain, Florentia Kaguelidou, and John N. van den Anker -- Pharmacotherapy for pulmonary hypertension / Robin H. Steinhorn -- Pharmacologic management of the opioid neonatal abstinence syndrome / Walter K. Kraft and John N. van den Anker -- Update on pain assessment in sick neonates and infants / Monique van Dijk and Dick Tibboel -- The impact of extracorporeal life support and hypothermia on drug disposition in critically ill infants and children / Enno D. Wildschut ... [et al.] -- Ethical issues in neonatal and pediatric clinical trials / Naomi Laventhal, Beth A. Tarini, and John Lantos N2 - Focuses on both general and specific aspects of neonatal and pediatric clinical pharmacology including ethics, pharmacogenomics, metabolomics, adverse drug reactions, pain medication, pulmonary hypertension and several other hot topics ER -