Evaluation of wet granulation process, granules and tablets properties using a new gentle wing high shear mixer granulator / Submitted by Mohamed Hassan Moustafa Fayed ; Supervised by Sayed Ibrahim Abdel-Rahman, (PhD, Professor of industrial pharmacy, faculty of pharmacy, Assiut University, Egypt), Mahrous Osman Ahmed, (PhD, Professor of industrial pharmacy, Dean of faculty of pharmacy, Assiut University, Egypt), Fars Bin Kead Alanazi, (PhD, Professor of pharmaceutics,faculty of pharmacy, King Saud University, Saudi Arabia), Hesham Mohamed Tawfeek, (PhD, Associate Professor and head industrial pharmacy department, faculty of pharmacy, Assiut University, Egypt)

By:

Fayed, Mohamed Hassan Moustafa [author.]

Material type: Text

TextLanguage: English Summary language: Arabic Publisher: 2017Description: xix, 236 pages,3 pages : illustrations ; 29 cmContent type:

text

Media type:

unmediated

Carrier type:

volume

Other title:

تقويم عملية التحبب الرطب و خواص الحبيبات و الاقراص باستخدام خلاط محبب جديد ذو جناح رقيق بقوة خلط عالية [Added title page title]

Subject(s):

DDC classification:

22 615.19 F.M.E

Dissertation note: Thesis (M.Sc.)- Assiut university, Faculty of Pharmacy, 2017. Abstract: The objectives of this research were divided into two parts. The first aimed to investigate the pharmaceutical wet granulation process and subsequent manufacturing of tablets of high dose drug formulation in a new gentle-wing high shear granulator using design of experiment approach. Moreover, the relationship between the granulation parameters (i.e. process and formulation variables) and the resulting granules and tablets have been investigated. The second part of this study aimed to explore the influence of process and formulation variables on the homogeneity and content uniformity of low dose drug formulations using gentle-wing high shear mixer during dry mixing, granulation and compression steps.

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Holdings
Item type	Current library	Collection	Call number	Status	Date due	Barcode
Thesis	Main library C3 THESIES	Pharmacy ( Pharmaceutical Technology )	615.19 F.M.E (Browse shelf(Opens below))	Not for loan		00016460

Supervised by Sayed Ibrahim Abdel-Rahman, (PhD, Professor of industrial pharmacy, faculty of pharmacy, Assiut University, Egypt), Mahrous Osman Ahmed, (PhD, Professor of industrial pharmacy, Dean of faculty of pharmacy, Assiut University, Egypt), Fars Bin Kead Alanazi, (PhD, Professor of pharmaceutics,faculty of pharmacy, King Saud University, Saudi Arabia), Hesham Mohamed Tawfeek, (PhD, Associate Professor and head industrial pharmacy department, faculty of pharmacy, Assiut University, Egypt)

A thesis submitted in partial fulfillment of the requirements for the degree of doctor of philosophy in pharmaceutical Sciences (industrial pharmacy)

Thesis (M.Sc.)- Assiut university, Faculty of Pharmacy, 2017.

The objectives of this research were divided into two parts. The first aimed to investigate the pharmaceutical wet granulation process and subsequent manufacturing of tablets of high dose drug formulation in a new gentle-wing high shear granulator using design of experiment approach. Moreover, the relationship between the granulation parameters (i.e. process and formulation variables) and the resulting granules and tablets have been investigated. The second part of this study aimed to explore the influence of process and formulation variables on the homogeneity and content uniformity of low dose drug formulations using gentle-wing high shear mixer during dry mixing, granulation and compression steps.

text in English, abstracts in Arabic and English.

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