Rationale of drug of choice a comparative analysis / P Nirmala, N Chidambaram

Includes bibliographical references and index.

Section 1: Autonomic Nervous System and Autacoids 1. Adrenergic Drugs 3 2. Alpha Blockers 13 3. Beta Blockers 20 4. Cholinergic Drugs 31 5. Anticholinergic Drugs 39 6. Skeletal Muscle Relaxants 49 7. Local Anesthetics 56 8. Histamine, Antihistamines and Leukotrienes 67 9. Serotonin Agonists and Antagonists 79 10. Prostaglandins 88 Section 2: Nonsteroidal Anti-inflammatory Drugs, Gout, Rheumatoid Arthritis and Central Nervous System 11. Nonsteroidal Anti-inflammatory Drugs 97 12. Pharmacotherapy of Gout 110 13. Rheumatoid Arthritis 117 14. Opioid Analgesics 122 15. Antiepileptic Drugs 133 16. General Anesthetics 144 17. Therapeutic Gases 158 18. Alcohol, Sedatives and Hypnotics 160 19. Cerebrodegenerative Disorders 169 20. Antipsychotics and Drugs in Bipolar Disorder 179 21. Antidepressants and Antianxiety Drugs 189 22. Drug Addiction 201 Section 3: Cardiovascular System 23. Antianginal Drugs and Drugs in Peripheral Vascular Disease 207 24. Pharmacotherapy of Hypertension 215 25. Drugs in Heart Failure 227 26. Antiarrhythmic Drugs 237 27. Diuretics and Antidiuretics 247 28. Anticoagulants, Thrombolytics and Antiplatelets 262 29. Hypolipidemic Drugs 275 30. Pharmacotherapy of Shock 287

31. Hematopoietic Agents 294 Section 4: Chemotherapy 32. General Principles of Antimicrobial Therapy 305 33. Sulfonamides, Trimethoprim, Quinolones, Chemotherapy of Urinary Tract Infection and Urinary Antiseptics 308 34. Beta Lactam Antibiotics (Penicillins, Cephalosporins and Carbapenems) 330 35. Aminoglycoside Antibiotics 356 36. Broad Spectrum Antibiotics 363 37. Macrolide and Miscellaneous Antibiotics 372 38. Chemotherapy of Sexually Transmitted Diseases 382 39. Chemotherapy of Malaria 387 40. Amebiasis, Giardiasis and Other Protozoal Infections 396 41. Chemotherapy of Tuberculosis and Leprosy 407 42. Anthelmintic Drugs 416 43. Antiviral Drugs 429 44. Antiretroviral Drugs 437 45. Antifungal Agents 447 46. Anticancer Drugs 461 47. Immunomodulators 488 Section 5: Endocrine Drugs 48. Introduction and Hypothalamic-Pituitary Axis 495 49. Thyroid and Antithyroid Drugs 501 50. Corticosteroids 507 51. Antidiabetic Drugs 51752. Estrogens and Progestins 536 53. Androgens 545 54. Agents Affecting Mineral Ion Homeostasis and Bone Turnover 550 Section 6: Environmental Toxicology 55. Chelating Agents 561 Section 7: Respiratory System 56. Antitussives, Mucolytics, Pharmacotherapy of Bronchial Asthma and Chronic Obstructive Pulmonary Disease 573 Section 8: Gastrointestinal Tract 57. Acid Peptic Disease and Gastroesophageal Reflux Disease 589 58. Antiemetics and Disorders of Bowel Motility 601 Section 9: Special Systems 59. Obstetric and Gynecological Pharmacology 619 60. Dermatological Pharmacology 648 61. Ocular Pharmacology 655 References 661 Index 673