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Molecular diagnostics : techniques and applications for the clinical laboratory / [edited by] Wayne W. Grody ... [et al.]

Contributor(s): Material type: TextTextPublisher: Amsterdam ; Boston : Academic Press, [2010]Copyright date: ©2010Description: ix, 484 pages , [23] pages of plates : illustartions (some color) ; 28 cmContent type:
  • text
Media type:
  • unmediated
Carrier type:
  • volume
ISBN:
  • 9780123694287 (hbk.)
  • 0123694280 (hbk.)
Subject(s): DDC classification:
  • 616.0756 22 M
Contents:
I. Introduction and Methodology Quantivative PCR: an introduction Signal Amplification Methods in Molecular Diagnostics The Lab-on-a-Chip Approach for Molecular Diagnostics Nucleic Extraction and Amplification General Procedures II. Quality Assurance, Regulatory, and Ethical Issues Billing and Reimbursement for Molecular Diagnostics Molecular Pathology and Infectious Diseases Ethical Considerations in Molecular Diagnostics Quality Control, Assurance, Identification and Standards III. Genetic Disease Molecular Testing for Cystic Fibrosis and CFTR-Related Conditions Carrier Testing for Neurogenetic Diseases Hemochromatosis Standards and Recommendations for Molecular Diagnostic Testing for Huntington Disease, the Autosomal Dominant Spinocerebellar Ataxias, and Friedreich Ataxia IV. Cancer The Role of Micro-RNAs in Cancer Molecular Diagnostics in the Evaluation of Cancer: Modern Concepts and Overview Gene Expression Analysis for Tumor Profiling GEA for TP Molecular Diagnostics of Hematopoetic Malignancies V. Infectious Diseases Viruses Hepatic B and C Viruses Molecular Diagnosis of Cytomegalovirus Molecular Detection of Multiple Respiratory Viruses Bacteria Molecular Methods for Identification and Characterization of Acinetobacter species Molecular Detection and Surveillance of Healthcare-Associated Infections Molecular Detection Of Group B Streptococcus Role of Molecular Techniques in the Epidemiologic Investigation Of Hospital-Acquired Infections Human Papilloma Virus and its Role in Cervical Carcinoma VI. Specialized Applications of Molecular Testing Molecular HLA Typing Methods Used in Clinical Laboratories Identification through DNA analysis in criminal and family relatedness investigations. VII. Pharmacogenetics Overview of Pharmacogenomics and Applications for the Modern Clinical Laboratory UDP-Glucuronosyltransferase 1A1 and the Glucuronidation in Oncology Applications and Hyperbilirubinemia Pharmacogenetics of P-450 Enzymes Pharmacogenomics of Thiopurine Methyl Transferase (TPMT): Importance in Monitoring of Mercaptopurine/Azathioprine Therapy
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Item type Current library Collection Call number Status Date due Barcode
Books Books Main library A11 Pharmacy ( Microbiology ) 616.0756 M (Browse shelf(Opens below)) Available 00009160

Includes bibliographical references and index.

I. Introduction and Methodology
Quantivative PCR: an introduction
Signal Amplification Methods in Molecular Diagnostics
The Lab-on-a-Chip Approach for Molecular Diagnostics
Nucleic Extraction and Amplification
General Procedures

II. Quality Assurance, Regulatory, and Ethical Issues
Billing and Reimbursement for Molecular Diagnostics
Molecular Pathology and Infectious Diseases
Ethical Considerations in Molecular Diagnostics
Quality Control, Assurance, Identification and Standards

III. Genetic Disease
Molecular Testing for Cystic Fibrosis and CFTR-Related Conditions
Carrier Testing for Neurogenetic Diseases
Hemochromatosis
Standards and Recommendations for Molecular Diagnostic Testing for Huntington Disease, the Autosomal Dominant Spinocerebellar Ataxias, and Friedreich Ataxia

IV. Cancer
The Role of Micro-RNAs in Cancer
Molecular Diagnostics in the Evaluation of Cancer: Modern Concepts and Overview
Gene Expression Analysis for Tumor Profiling GEA for TP
Molecular Diagnostics of Hematopoetic Malignancies

V. Infectious Diseases
Viruses
Hepatic B and C Viruses
Molecular Diagnosis of Cytomegalovirus
Molecular Detection of Multiple Respiratory Viruses

Bacteria
Molecular Methods for Identification and Characterization of Acinetobacter species
Molecular Detection and Surveillance of Healthcare-Associated Infections
Molecular Detection Of Group B Streptococcus
Role of Molecular Techniques in the Epidemiologic Investigation Of Hospital-Acquired Infections
Human Papilloma Virus and its Role in Cervical Carcinoma

VI. Specialized Applications of Molecular Testing
Molecular HLA Typing Methods Used in Clinical Laboratories
Identification through DNA analysis in criminal and family relatedness investigations.

VII. Pharmacogenetics
Overview of Pharmacogenomics and Applications for the Modern Clinical Laboratory
UDP-Glucuronosyltransferase 1A1 and the Glucuronidation in Oncology Applications and Hyperbilirubinemia
Pharmacogenetics of P-450 Enzymes
Pharmacogenomics of Thiopurine Methyl Transferase (TPMT): Importance in Monitoring of Mercaptopurine/Azathioprine Therapy

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