Marks' essentials of medical biochemistry : a clinical approach / Michael Lieberman, PhD, Distinguished Teaching Professor, Department of Molecular Genetics, Biochemistry, and Microbiology, University of Cincinnati, College of Medicine, Cincinnati, Ohio, Alisa Peet, MD, Associate Professor of Clinical Medicine, Director, Medicine Clerkship, Department of Internal Medicine, Temple University, School of Medicine, Philadelphia, Pennsylvania.

By:

Lieberman, Michael, 1950- [author.]

Contributor(s):

Peet, Alisa [author.]

Material type: Text

TextPublisher: Philadelphia : Wolters Kluwer, [2015]Edition: Second editionDescription: ix, 622 pages : illustrations (some color) ; 28 cmContent type:

text

Media type:

unmediated

Carrier type:

volume

ISBN:

9781451190069 (pbk.)

Other title:

Essentials of medical biochemistry

Uniform titles:

Marks' essential medical biochemistry

Related works:

Lieberman, Michael, 1950- Marks' basic medical biochemistry. Based on (work)

Subject(s):

DDC classification:

612.015 23 L.M.M

LOC classification:

QP514.2 .L54 2015

NLM classification:

QU 34

Online resources:

Abstrcat

Contents:

An overview of fuel metabolism -- Water, acids, bases, and buffers -- Structures of the major compounds of the body -- Amino acids in proteins -- Structure-function relationships in proteins -- Enzymes as catalysts -- Regulation of enzymes -- Cell structure and signaling by chemical messengers -- Structure of the nucleic acids -- Synthesis of DNA -- Transcription: synthesis of RNA -- Translation: synthesis of proteins -- Regulation of gene expression -- Use of recombinant DNA techniques in medicine -- Cellular bioenergetics: ATP and O2 -- Tricarboxylic acid cycle -- Oxidative phosphorylation, mitochondrial function, and oxygen radicals -- Generation of ATP from glucose: glycolysis -- Oxidation of fatty acids and ketone bodies -- Basic concepts in the regulation of fuel metabolism by insulin, glucagon, and other hormones -- Digestion, absorption, and transport of carbohydrates -- Formation and degradation of glycogen. Pathways of sugar metabolism: fructose, galactose, pentose phosphate pathway, and ethanol metabolism -- Synthesis of glycosides, lactose, glycoproteins, and glycolipids and proteoglycans -- Gluconeogenesis and maintenance of blood glucose levels -- Digestion and transport of dietary lipids -- Synthesis of fatty acids, triacylglycerols, eicosanoids, and the major membrane lipids -- Cholesterol absorption, synthesis, metabolism and fate -- Integration of carbohydrate and lipid metabolism -- Protein digestion and amino acid absorption -- Fate of amino acid nitrogen: urea cycle -- Synthesis and degradation of amino acids and amino acid derived products -- Tetrahydrofolate, vitamin B12, and S-adenosylmethionine -- Purine and pyrimidine metabolism -- Intertissue relationships in the metabolism of amino acids.

Summary: Marks’ Essentials of Medical Biochemistry takes a patient-oriented approach that links biochemistry to physiology and pathophysiology, allowing students to apply fundamental concepts to the practice of medicine. Based on the established text, Marks’ Basic Medical Biochemistry, Marks’ Essentials is streamlined to focus only on the most essential biochemical concepts, while maintaining intuitively organized chapters centered on hypothetical patient vignettes and helpful icons for smooth navigation. • Full-color illustrations of chemical structures and biochemical pathways elucidate core concepts and enhance understanding of the text • Hypothetical patient vignettes ensure clinical relevance and help connect biochemistry to human health and disease • Helpful icons guide you through each chapter and identify key concepts such as signs and symptoms, clinical pearls, treatment options and outcomes, and more • Chapter Outlines and Key Points allow readers to preview and review chapter content • End-of-Chapter Review Questions and Summary Disease Tables highlight the take-home messages and reinforce knowledge

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Holdings
Item type	Current library	Collection	Call number	Status	Date due	Barcode
Books	Main library A10	Dental ( Supplementary General Sciences )	612.015 L.M.M (Browse shelf(Opens below))	Available		00014284

Includes indexes.

dental bookfair2016

Preceded by: Marks' essential medical biochemistry / Michael Lieberman, Allan Marks, Colleen Smith. c2007.

Based on: Marks' basic medical biochemistry / Michael Lieberman, Allan Marks, Alisa Peet. 4th ed. c2013.

An overview of fuel metabolism --
Water, acids, bases, and buffers --
Structures of the major compounds of the body --
Amino acids in proteins --
Structure-function relationships in proteins --
Enzymes as catalysts --
Regulation of enzymes --
Cell structure and signaling by chemical messengers --
Structure of the nucleic acids --
Synthesis of DNA --
Transcription: synthesis of RNA --
Translation: synthesis of proteins --
Regulation of gene expression --
Use of recombinant DNA techniques in medicine --
Cellular bioenergetics: ATP and O2 --
Tricarboxylic acid cycle --
Oxidative phosphorylation, mitochondrial function, and oxygen radicals --
Generation of ATP from glucose: glycolysis --
Oxidation of fatty acids and ketone bodies --
Basic concepts in the regulation of fuel metabolism by insulin, glucagon, and other hormones --
Digestion, absorption, and transport of carbohydrates --
Formation and degradation of glycogen. Pathways of sugar metabolism: fructose, galactose, pentose phosphate pathway, and ethanol metabolism --
Synthesis of glycosides, lactose, glycoproteins, and glycolipids and proteoglycans --
Gluconeogenesis and maintenance of blood glucose levels --
Digestion and transport of dietary lipids --
Synthesis of fatty acids, triacylglycerols, eicosanoids, and the major membrane lipids --
Cholesterol absorption, synthesis, metabolism and fate --
Integration of carbohydrate and lipid metabolism --
Protein digestion and amino acid absorption --
Fate of amino acid nitrogen: urea cycle --
Synthesis and degradation of amino acids and amino acid derived products --
Tetrahydrofolate, vitamin B12, and S-adenosylmethionine --
Purine and pyrimidine metabolism --
Intertissue relationships in the metabolism of amino acids.

Marks’ Essentials of Medical Biochemistry takes a patient-oriented approach that links biochemistry to physiology and pathophysiology, allowing students to apply fundamental concepts to the practice of medicine. Based on the established text, Marks’ Basic Medical Biochemistry, Marks’ Essentials is streamlined to focus only on the most essential biochemical concepts, while maintaining intuitively organized chapters centered on hypothetical patient vignettes and helpful icons for smooth navigation.
• Full-color illustrations of chemical structures and biochemical pathways elucidate core concepts and enhance understanding of the text
• Hypothetical patient vignettes ensure clinical relevance and help connect biochemistry to human health and disease
• Helpful icons guide you through each chapter and identify key concepts such as signs and symptoms, clinical pearls, treatment options and outcomes, and more
• Chapter Outlines and Key Points allow readers to preview and review chapter content
• End-of-Chapter Review Questions and Summary Disease Tables highlight the take-home messages and reinforce knowledge

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