Peptide and protein drug analysis / edited by Ronald E. Reid.

pt. 1. Strategies -- Practical principles of protein design / Ronald E. Reid and Patrick L Franchini -- Peptidomimetric and nonpeptide drug discovery: chemical nature and biological tragets / Tomi K. Sawyer -- Structure prediction and molecular modeling / Robin E.J. Munro and William R. Taylor -- Chemical synthesis of peptides / Henriette A. Remmer and Gregg B. Fields -- Chemical synthesis of proteins / Graham J. Cotton, Maria C. Pietanza, and Tom W. Muir -- Introduction of unnatural amino acids into proteins / Scott A. Lesley -- Combinatorial chemistry and the structure-function analysis of proteins / Rachel L. Winston and Michael C. Fitzgerald -- Folding polypeptides for drug production and discovery / Elizabeth Strickland, Philip J. Thomas, and Ming Li -- Protein and peptide chemical and physical stability / Bernard N. Violand and Ned R. Siegel -- Bioinformaticics and computational chemistry in molecular design: recent advances and their applications / Jin Li and Barry Robson --

pt. 2. Chemical analysis -- High pressure liquid chromatography of peptides and proteins / Marie-Isabel Aquilar -- Practical aspects of peptide and protein analysis by capillary electrophoresis / Nicole J. Munro, Andreas Hühmer, and James P. Landers -- Gel electrophoresis of peptides and proteins / Michael J. Dunn -- Carbohydrate analysis of glycoproteins and glycopeptides / Nigel Jenkins, Pir M. Shah, and Lorraine D. Buckberry -- Protein sequence analysis / Hsieng S. Lu, Lee Anne Merewether, and Michael F. Rohde -- Mass spectrometry / Vic Garner -- pt. 3. Functional analysis -- Protein and peptide immunoassays / Anthony B. Chen -- Pharmacogenomics / Ann K. Daly and Jane Grove -- Analysis of polypeptide bioactivity / David C. Wood, Q. Khai Huynh, and Joseph B. Monahan -- Pharmacokinetics and pharmacodynamics of protein therapeutics / Rene Braeckman -- Approaches to validating the identity of peptides and proteins / Ian R. Tebbett and Nancy D. Denslow -- pt. 4. Structural analysis --

Solution structure determination of proteins by nuclear magnetic resonance spectroscopy / Nicholas J. Skelton and Walter J. Chazin -- NMR studies of protein-peptide complexes: example from the calmodulin system / A. Joshua Wand, Jeffrey L. Urbauer, Mark R, Ehrhardt, and Andrew L. Lee -- Circular dichroism and fourier transform infra-red analysis of polypeptide conformation / Graeme J. Anderson -- Electron paramagnetic resonance of peptides and proteins / Derek Marsh -- UV-visible and fluorescence spectroscopy of polypeptides and proteins / G.M. Anantharamaiah, Vinod K. Mishra, Geeta Datta, and Herbert C. Cheung -- Ultracentrifugation, light, x-ray-, and neutron-scattering of peptides, proteins, and nucleic acids in solution / Henryk Eisenberg.