Pharmaceutical inhalation aerosol technology / edited by Anthony J. Hickey.

Includes bibliographical references and index.

Factors governing aerosol deposition and targeting in the lung - physiology of the airways, Anthony J. Hickey and David C. Thompson, pharmacology of therapeutic aerosols, David C. Thompson, targeting by deposition, Igor Gonda, drug targeting to the lung - chemical and biochemical considerations, Peter A. Crooks; methods of generation, administration, and characterization of aerosols - theoretical principles and devices used to generate aerosols for research, Keng H. Leong, the design and development of inhalation drug delivery systems, Paul J. Atkins, et al, aerosol-filling equipment for the preparation of pressurized pack pharmaceutical formulations, Christophe Sirand, et al, methods of aerosol particle size characterization, Anthony J. Hickey, summary of common approaches to pharmaceutical aerosol administration, Anthony J. Hickey; clinical aspects of aerosol administration and future perspectives - therapeutic aerosols - an overview from a clinical perspective, F. Charles Hiller, aerosolized pentamidine for treatment and prophylaxis of pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome, A. Bruce Montgomery, modulated drug therapy with inhalation aerosols, Ralph W. Niven.

Covers all aspects of aerosol therapy and offers logical development of important concepts to organize the knowledge in this multidisciplinary field. The book discusses the physiologic, pharmacologic, metabolic and physicochemical factors influencing the effective use of aerosols.