Clinicians' guide to Aspirin / Antony Bayer.

Includes bibliographical references and index.

Historical background -- Early history -- Reverend Mr. Edward Stone -- 19th century -- Felix Hoffmann and the Bayer Company -- Antithrombotic effects and prevention of vascular events -- Mechanism of action -- Pharmacokinetics and pharmaceutical considerations -- Physicochemical properties -- Pharmacokinetics -- Which preparation? -- Mode of action and pharmacological effects -- Mode of action -- Therapeutic use for inflammation, pain and fever -- Inflammation -- Pain -- Fever -- Therapeutic use in vascular diseases -- Primary prevention of occlusive cardiovascular disease -- Secondary prevention of occlusive cardiovascular disease -- Maintenance of vascular grafts and arterial patency -- What dose? -- Miscellaneous therapeutic uses -- Prevention of colorectal cancer -- Prevention of other cancers -- Prevention of cataract -- Pregnancy -- Prevention of cognitive decline and dementia -- Other possible therapeutic uses -- Adverse effects and toxicity -- Gastrointestinal side effects -- Intracranial bleeding -- Hypersensitivity -- Reye's syndrome -- Other adverse effects -- Toxicity -- Contraindications and drug interactions -- Contraindications and precautions -- Use in particular patient groups -- Interactions with other drugs.