000			03124cam a2200433 i 4500
001			18114191
003			OSt
005			20160228123546.0
008			140414t20152015nyua 000 0 eng
010			_a 2014010851
020			_a9780815342441 (paperback)
020			_a0815342446 (paperback)
040			_aDLC _beng _cDLC _erda _dDLC
042			_apcc
050	0	0	_aQH604.2 _b.L56 2015
082	0	0	_a571.74 _223 _bL.W.C
084			_aSCI000000 _aSCI008000 _aSCI017000 _2bisacsh
100	1		_aLim, Wendell, _eauthor.
245	1	0	_aCell signaling : _bprinciples and mechanisms / _cWendell Lim, Bruce Mayer, Tony Pawson.
264		1	_aNew York : _bGarland Science, Taylor & Francis Group, _c[2015]
264		4	_c©2015
300			_axvi, 400 pages : _bcolor illustrations ; _c28 cm + _e1 poster (color illustrations, both sides ; 71 x 53 cm)
336			_atext _2rdacontent
337			_aunmediated _2rdamedia
338			_avolume _2rdacarrier
500			_apharmacy bookfair2016
505	0		_aIntroduction to cell signaling -- Principles and mechanisms of protein interactions -- Signaling enzymes and their allosteric regulation -- Role of post-translational modifications in signaling -- Subcellular localization of signaling molecules -- Second messengers: small signaling mediators -- Membranes, lipids, and enzymes that modify them -- Information transfer across the membrane -- Regulated protein degradation -- Modular architecture and evolution of signaling proteins -- Information processing by signaling devices and networks -- How cells make decisions -- Methods for studying signaling proteins and networks.
520			_a"Cell Signaling presents the principles and components that underlie all known signaling mechanisms. The book provides undergraduate and graduate biology students with the tools needed to make sense of the array of specific pathways used by the cell to communicate. As each concept is explained, numerous examples derived from known signaling mechanisms are used to illustrate the key points. It describes basic signaling mechanisms such as protein interactions, changes in enzyme activity, post-translational modifications, subcellular localization of signaling molecules, and small diffusible signaling mediators. The book also explores the components of signaling pathways and how they are "wired" into pathways and circuits that can process information. The book concludes with a unique chapter that presents extended examples in which specific problems encountered in signaling are introduced and solved, followed by a chapter on methods"-- _cProvided by publisher.
650		0	_aCell interaction.
650		0	_aCellular signal transduction.
650		7	_aSCIENCE / General. _2bisacsh
650		7	_aSCIENCE / Life Sciences / Biology / General. _2bisacsh
650		7	_aSCIENCE / Life Sciences / Cytology. _2bisacsh
700	1		_aMayer, Bruce, _eauthor.
700	1		_aPawson, T. , _eauthor.
906			_a7 _bcbc _corignew _d1 _eecip _f20 _gy-gencatlg
942			_2ddc _cBK
999			_c10369 _d10369