000 04044cam a22004934i 4500
999 _c10410
_d10410
001 15634211
005 20200915134542.0
008 090219s2009 nyua b 001 0 eng
010 _a 2009007532
016 7 _a101496762
_2DNLM
020 _a9781420088496 (hardcover : alk. paper)
020 _a1420088491 (hardcover : alk. paper)
035 _a(OCoLC)ocn311059894
040 _aDNLM/DLC
_cDLC
_dBTCTA
_dBAKER
_dYDXCP
_dNLM
_dC#P
_dBWX
_dDLC
_erda
042 _apcc
043 _an-us---
050 0 0 _aRS189
_b.N476 2009
082 0 0 _a615.1
_222
_bN
245 0 0 _aNew drug approval process /
_cedited by Richard A. Guarino.
250 _afifth edition.
264 1 _aNew York :
_bInforma Healthcare,
_c[2010]
300 _axviii, 529 pages :
_billustrations ;
_c24 cm
336 _2rdacontent
_atext
337 _2rdamedia
_aunmediated
338 _2rdacarrier
_avolume
490 1 _aDrugs and the pharmaceutical sciences ;
_vv. 190
500 _apharmacy bookfair2016
504 _aIncludes bibliographical references and index.
505 0 _a Front Cover -- Preface -- Contents -- PART I ADMINISTRATIVE GUIDELINES FOR NEW PRODUCT DEVELOPMENT -- 1. Drug Development Teams -- 2. FDA Approvable Indications and Other Considerations -- 3. Data Presentation for Global Submissions: Text and Tabular Exposition-CTD Format -- 4. Technology Change-Enabling Clinical Research and Drug Development Processes -- 5. Working with a Contract Research Organization (CRO) -- 6 Industry and FDA Liaison -- PART II GLOBAL REGULATORY SUBMISSION OF DRUGS, BIOLOGICS AND DEVICES FOR NEW PRODUCT APPROVAL -- 7. Nonclinical Drug Development: Pharmacology, DrugMetabolism, and Toxicology -- 8. The Investigational New Drug Application (IND), the Investigational Medicinal Product Dossier (IMPD) and the Investigator's Brochure (IB) -- 9. New Product Applications for Global Pharmaceutical Product Approvals: U.S. NDA Vs. Global CTD Formats -- 10. Abbreviated and Supplemental New Drug Applications (ANDAs and SNDAs) -- 11. The CTD and eCTD for the Registration of Pharmaceuticals for Human Use -- 12. The Biologic License Application -- 13. Chemistry, Manufacturing, and Control (ICH Quality Guidelines) -- 14. New Medical Device Approval Process in the United States -- 15. Orphan Drugs -- PART III DEVELOPING CLINICAL RESEARCH TRIALS -- 16. Clinical Research Protocols -- 17. Institutional Review Board/Independent Ethics Committee and Informed Consent: Protecting Research Subjects in the U.S. and Foreign Clinical Trials -- 18. HIPAA: A New Requirement to the Clinical Study Pr -- 19. Adverse Events and Reactions: Etiology, Drug Interactions, Collection, andReporting -- 20. Biostatistics in Pharmaceutical Product Development Facts, Recommendations, and Solutions -- PART IV GLOBAL REGULATIONS FOR GOOD CLINICAL PRACTICES (GCP) -- 21. CFR/ICH/EU GCP Obligations of Investigators, Sponsors, andMonitors -- 22. Quality Assurance. 23. Managing and Monitoring Clinical Trials -- 24. European CT Directive: Implementation and Update -- PART V SPECIFIC AREAS OF NEW PRODUCT SUBMISSIONS -- 25. Combination Products -- 26. The Current State of GXP in China -- Acronyms and Initialisms -- Index.
650 0 _aDrug approval
_zUnited States.
650 0 _aDrugs
_xTesting
_xStandards.
650 0 _aDrugs
_xTesting
_xGovernment policy
_zUnited States.
650 0 _aNew products
_xGovernment policy
_zUnited States.
650 1 2 _aDrug Evaluation
_xstandards
_zUnited States.
_98637
650 2 2 _aClinical Trials as Topic
_xstandards
_zUnited States.
650 2 2 _aDrug Approval
_zUnited States.
700 1 _aGuarino, Richard A.,
_d1935-,
_eeditor.
830 0 _aDrugs and the pharmaceutical sciences ;
_vv. 190.
856 _3Abstract
_uhttp://repository.fue.edu.eg/xmlui/handle/123456789/1816
906 _a7
_bcbc
_corignew
_d1
_eecip
_f20
_gy-gencatlg
942 _2ddc
_cBK