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010 _a2019026118
020 _a9781496385024
020 _a1496385020
020 _a9781975139032
020 _a1975139038
020 _z9781496385871
040 _aNLM
_beng
_erda
_cNLM
_dOCLCO
_dDLC
_dNTU
_dMOP
_dYDX
_dOCLCO
_dOCLCF
_dOCLCA
_dEG-NcFUE
042 _apcc
050 0 0 _aRS403
_b.P75 2020
082 0 4 _223
_a616.0756
_bF
245 0 0 _aFoye's principles of medicinal chemistry /
_c[edited by] Victoria F. Roche, S. William Zito, Thomas L. Lemke, David A. Williams
246 1 _aPrinciples of medicinal chemistry
250 _aEighth edition
264 1 _aPhiladelphia :
_bWolters Kluwer,
_c[2020]
264 4 _c©2020
300 _axix, 1626 pages :
_billustrations ;
_c29 cm
336 _atext
_btxt
_2rdacontent
337 _aunmediated
_bn
_2rdamedia
338 _avolume
_bnc
_2rdacarrier
504 _aIncludes bibliographical references and indexes
505 0 _aPart I  Principles CHAPTER 1  Introduction to Medicinal Chemistry CHAPTER 2  Foundational Principles and Functional Group Impact on Activity CHAPTER 3  Drug Metabolism CHAPTER 4  Membrane Drug Transporters CHAPTER 5  Principles of Biotechnology-Derived Drugs Part II  Receptor Targets CHAPTER 6  G Protein–Coupled Receptors CHAPTER 7  Nuclear Receptors CHAPTER 8  Ion Channel Receptors CHAPTER 9  Enzyme/Catalytic Receptors Part III  Pharmacodynamic Agents Section 1 Drugs Impacting the Central Nervous System CHAPTER 10  Drugs Used to Treat Neuromuscular Disorders CHAPTER 11  Drugs Used to Treat Mental, Behavioral, and Cognitive Disorders CHAPTER 12  Drugs Used to Induce/Support Sedation or Anesthesia CHAPTER 13  Drugs Used to Treat Seizure Disorders Section 2 Drugs Impacting Pain Perception CHAPTER 14  Drugs Used to Treat Pain: Centrally Acting Agents CHAPTER 15  Drugs Used to Treat Pain: Peripherally Acting Agents Section 3 Drugs Impacting the Cardiovascular System CHAPTER 16  Drugs Used to Treat Cardiac Disorders CHAPTER 17  Drugs Used to Treat Hypertensive/Hypotensive Disorders CHAPTER 18  Drugs Used to Treat Coagulation Disorders CHAPTER 19  Drugs Used to Treat Dyslipidemic Disorders Section 4 Drugs Impacting Hormonal Systems CHAPTER 20  Drugs Used to Treat Diabetic Disorders CHAPTER 21  Drugs Used to Treat Inflammatory and Corticosteroid Deficiency Disorders CHAPTER 22  Drugs Used to Treat Thyroid Disorders CHAPTER 23  Drugs Used to Treat Calcium-Dependent Disorders CHAPTER 24  Drugs Used to Advance Men’s and Women’s Health Section 5 Drugs Impacting Immune, Gastrointestinal and Genitourinary Systems CHAPTER 25  Drugs Used to Treat Allergic Disorders CHAPTER 26  Drugs Used to Treat Gastrointestinal and Genitourinary Disorders Section 6 Drugs Impacting Ocular, Nasal and Pulmonary Systems CHAPTER 27  Drugs Used to Treat Ocular and Nasal Congestion Disorders CHAPTER 28  Drugs Used to Treat Pulmonary Disorders Section 7 Drugs Impacting Infectious and Neoplastic Disease Processes CHAPTER 29  Drugs Used to Treat Bacterial Infections CHAPTER 30  Drugs Used to Treat Viral Infections CHAPTER 31  Drugs Used to Treat Fungal Infections CHAPTER 32  Drugs Used to Treat Parasitic Infections CHAPTER 33  Drugs Used to Treat Neoplastic Diseases Section 8 Therapeutic Biologics CHAPTER 34  Biologics Used in the Treatment of Disease Part IV  Disease State Management CHAPTER 35  Coronary Artery Disease CHAPTER 36  Rheumatoid Arthritis CHAPTER 37  Nutrition and Obesity Appendix A  cLogP and cLogDpH 7.4 Values of Selected Drugs Appendix B  Predicted pKa Values of Commonly Prescribed Drugs Appendix C  pH Values of Biological Fluids Subject Index Drug Index
520 _a"With expert contributions from experienced educators, research scientists and clinicians, Foye's Principles of Medicinal Chemistry, Eighth Edition is an invaluable resource for professional students, graduate students and pharmacy faculty alike . This 'gold standard' text explains the chemical basis of drug action, emphasizing the structure-activity relationships, physicochemical-pharmacokinetic properties, and metabolic profiles of the most commonly used drugs"--
_cProvided by publisher
650 0 _aPharmaceutical chemistry
650 1 2 _aChemistry, Pharmaceutical
700 1 _aRoche, Victoria F.,
_eeditor
700 1 _aZito, S. William,
_eeditor
700 1 _aLemke, Thomas L.,
_eeditor
700 1 _aWilliams, David A.,
_d1938-
_eeditor
942 _2ddc
_cBK