000			02023cam a22003614a 4500
999			_c12729 _d12729
001			11802722
005			20210302131540.0
008			991005s2000 nyua b 001 0 eng d
010			_a 99051474
020			_a0824782100 (alk. paper)
040			_aEG-NcFUE _cEG-NcFUE _erda
042			_apcc
050	0	0	_aRS201.E87 _bE96 2000
082	0	0	_221 _a615.19 _bE
245	0	0	_aExcipient toxicity and safety / _cedited by Myra L. Weiner, Lois A. Kotkoskie.
264		1	_aNew York : _bM. Dekker, _c[2000]
264		4	_a©2000.
300			_ax, 370 pages : _billustrations ; _c24 cm.
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
440		0	_aDrugs and the pharmaceutical sciences ; _vv.103
504			_aIncludes bibliographical references and index.
505	0		_apt. 1. Introduction to excipients -- What are excipients? -- Purity of excipients -- History of excipient safety and toxicity -- Regulation of pharmaceuicatl excipients -- pt. 2. Safety evaluation of pharamceutical excipients -- Development of safety evaluation guidelines -- Routes of exposure: oral -- Routes of exposure: topical and transdermal -- Routes of exposure: inhalation and intranasal -- Routes of exposure: parenteral -- Routes of exposure: other -- pt. 3. Risk assessment of excipients -- Toxicokinetics and hazard identification -- Exposure assessment -- Risk assessment and risk communication -- pt. 4. Future issues -- Harmonization of excipient standards.
650		0	_aExcipients _xToxicology.
700	1		_aWeiner, Myra L., _d1944- _eauthor
700	1		_aKotkoskie, Lois A. _eauthor
856	4	2	_3Publisher description _uhttp://www.loc.gov/catdir/enhancements/fy0647/99051474-d.html
906			_a7 _bcbc _corignew _d1 _eocip _f19 _gy-gencatlg
942			_2ddc _cBK