000			03083pam a2200385 i 4500
999			_c12876 _d12876
001			1090062
005			20210307104519.0
008			921217s1993 nyua b 001 0 eng c
010			_a 92048325
020			_a0824788060 (alk. paper)
040			_aDNLM/DLC _cDLC _dDLC _erda
050	0	0	_aRE994 _b.O62 1993
060			_aW1 DR893B v.58 _aWW 166 O603
082	0	0	_a617.7061 _222 _bO.
245	0	0	_aOphthalmic drug delivery systems / _cedited by Ashim K. Mitra.
264		1	_aNew York : _bMarcel Dekker Inc., _c[1993]
264		4	_c©1993
300			_axii, 502 pages : _billustrations (black and white) ; _c26 cm
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
490	1		_aDrugs and the pharmaceutical sciences ; _v58
504			_aIncludes bibliographical references and index.
505	0		_aOverview of ocular drug delivery and iatrogenic ocular cytopathologies / Patrick M. Hughes and Ashim K. Mitra -- Ocular anatomy and physiology relevant to ocular drug delivery / James C. Robinson -- Precorneal, corneal, and postcorneal factors / Vincent H.L. Lee -- Ocular pharmacokinetics/pharmacodynamics / Ronald D. Schoenwald -- Cell cultures to assess corneal permeability / Jiahorng Liaw and Joseph R. Robinson -- Animal pharmacokinetic studies / Arto Urti and Lotta Salminen -- Disease state models / Lotta Salminen and Arto Urti -- Mathematical models of ocular drug transport and disposition / Kenneth J. Himmelstein -- Conventional systems in opthalmic drug delivery / Orest Olejnik -- Mucoadhesive polymers in ocular drug delivery / Ramesh Krishnamoorthy and Ashim K. Mitra -- Ocular inserts / Rajan Bawa -- Corneal collagen shields for ocular delivery / James M. Hill [and others] -- Particulates (nanoparticles and microparticles) / Jorg Kreuter -- Advanced corneal delivery systems: liposomes / Nigel M. Davies [and others]. (cont) Chemical delivery systems with enhanced pharmacokinetic properties / Ronald D. Schoenwald -- Ocular iontophoresis / James M. Hill, Richard J. O'Callaghan and Jeffery A. Hobden -- New ophthalmic delivery system / Mark C. Richardson and Peter H. Bentley -- Ocular penetration enhancers / Jiahorng Liaw and Joseph R. Robinson -- Intracameral, intravitreal, and retinal drug delivery / Joel A. Schulman and Gholam A. Peyman -- Systemic delivery of drugs for ophthalmic diseases / Phillip R. Mayer -- Peptide and protein therapeutics in the eye / Randall J. Erb -- Ocular delivery of peptides and proteins / Ramesh Krishnamoorthy and Ashim K. Mitra -- Regulatory considerations / Robert E. Roehrs.
650		0	_aOphthalmic drugs.
650		0	_aDrug delivery systems.
650		2	_aEye diseases _xdrug therapy.
650		2	_aOphthalmic Solutions _xadministration & dosage.
700	1		_aMitra, Ashim K., _d1954-, _eeditor.
830		0	_aDrugs and the pharmaceutical sciences ; _vv. 58.
906			_a7 _bcbc _corignew _d1 _eocip _f19 _gy-gencatlg
942			_2ddc _cBK