000			02091nam a22003017i 4500
999			_c12931 _d12931
005			20210309133231.0
008			210309s2009 su a|||| bm|| 00| 0 eng d
040			_aEG-NcFUE _erda
041	0		_aeng _bara _beng
082	0	4	_222 _a616.238061 _bA.H.D
100	1		_933870 _aAodah, Alhassan Hamood Yahya, _eauthor.
245			_aDesign and evaluation of chronotherapeutic drug delivery systems for the treatment of nocturnal asthma / _cpresented by Alhassan Hamood Yahya Aodah.
246	1	5	_aتصميم و تقييم نظم إيتاء دوائي للعلاج الإيقاعي الزمني للربو الليلي
264		1	_c2009.
300			_axxi, 118 pages, 8 pages : _billustrations (some color); _c29 cm
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
502			_aThesis (M. Sc. Pharmaceutics)-- college of pharmacy, King Saud University, 2009.
504			_aIncludes bibliographical references.
520	3		_aChronobiology is the scientific study of biologic rhythms and their underlying mechanisms. Application of the principles of chronobiology may help in disease prevention, aid in early diagnosis and treatment, and reduce overall health care costs. Chronopharmacokinetic studies have been reported for many drugs in an attempt to explain chronopharmacological phenomena and demonstrate that the time of administration is a possible factor of variation in the pharmacokinetics of a drug. Chronotherapeutics is defined as a treatment system where the in-vivo drug availability has been timed in accordance to cyclic rhythms of drug related biological phenomena to create maximum benefit minimizing harm. A number of common diseases are affected by chronobiology. Such diseases include angina, rheumatoid arthritis, allergic rhinitis, hypertension and cancer.
546			_aText in English, abstracts in Arabic and english.
650		0	_aAsthma _xTreatment _xDrug therapy
650		0	_aChronotherapeutic drugs _xEvaluation
650		0	_aPharmaceutical chemistry
942			_2ddc _cTHESIS