000			03024nam a22003377i 4500
999			_c12935 _d12935
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008			210310s2016 fg a|||| |||| 00| 0 eng d
020			_a9791095285014
040			_aEG-NcFUE _beng _dEG-NcFUE _erda
082	0	4	_223 _a615.19005 _bC
245	0	0	_aCapsules : Fields of Application & Industrial Technologies / _cEric Levacher, Jean-Luc Blondeau, Yves Bogaerts, Frederique Bordes-Picard, Eloi Brosseau, Bruno Cocheteux, Thersia Kuntz.
250			_aFirst edition
264		1	_a[Farance] : _bGroup IMT, _c[2016]
264		4	_c©2016
300			_a108 pages : _billustrations (chiefly color) ; _c24 cm
336			_2rdacontent _atext _btxt
337			_2rdamedia _aunmediated _bn
338			_2rdacarrier _avolume _bnc
505	0		_aPart 1 – Capsule Manufacture 1. INTRODUCTION 1.1. Definition 1.2. Capsule appearance 1.3. Composition 2. SPECIFICATIONS 2.1. Dimensions, capacities 2.2. Moisture content 2.3 Disintegration time 3. CAPSULE MANUFACTURE 3.1. Manufacturing process 3.2 Manufacturing inspections Part 2 – Fields of application 1. CAPSULE FILLING PRODUCTS 2. CAPSULES FOR SPECIFIC APPLICATIONS 2.1. Modified release 2.2. Capsules for pulmonary or nasal dispensation systems 2.3. Liquid formulations in capsules 2.4. Other technologies 3. FACING UP TO CURRENT CHALLENGES 3.1. Patient centric design 3.2. Quality by design and industrial efficiency Part 3 – Industrial implementation 1. CAPSULE FILLING CYCLE 1.1. Orientation and opening 1.2. Filling 1.3. Closing full capsules 1.4. Ejection 2. ALTERNATING MACHINES 2.1. General work flow 3. CONTINUOUS MACHINES 3.1. Single turret principle 3.2. Multiple turret principle 4. DOSING TECHNIQUES 4.1. Powder dosing 4.2. Micropellet filling 4.3. Solid unit form filling 4.4. Micotablet filling 4.5. Liquid and semi-solid filling 5. CONTROL SYSTEMS 5.1. Individual control of powder dosing with strain gauges 5.2. Individual control of pellet dosing 5.3. Individual camera control of microtablet dosing 5.4. Actual weight inspection systems 6. INSTALLATION / CONFIGURATION OF THE CAPSULE FILLING MACHINE 6.1. Standard 6.2. Through the wall 6.3. Modular systems 7. SORTING SYSTEMS / MACHINE EXIT INSPECTION 7.1. Elimination of deformed capsules 7.2. Elimination of empty or part-filled capsules 7.3. Metal detectors 8. CONTAINMENT 8.1. Containment problem 8.2. High-containment in capsule filling 8.3. Cleaning 9. SUBSEQUENT CAPSULE PROCESSING 9.1. Sealing / wrapping 9.2. Enteric film coating 10. TROUBLESHOOTING 10.1. General 10.2. Faults and diagnosis
650		0	_aPharmaceutical technology
650		0	_aPharmaceutical industry
700	1		_aLevacher, Eric, _eauthor.
700	1		_aBlondeau, Jean-Luc, _eauthor.
700	1		_aBogaerts, Yves, _eauthor.
700	1		_aPicard, Frederique Bordes, _eauthor.
700	1		_aBrosseau, Eloi, _eauthor.
700	1		_aCocheteux, Bruno, _eauthor.
700	1		_aKuntz, Thersia, _eauthor.
942			_2ddc _cBK