000 02462cam a22003614i 4500
999 _c1890
_d1890
001 13927077
005 20230508094649.0
008 050412s2005 enka b 001 0 eng
020 _a052184729X (hbk.)
040 _aDLC
_cDLC
_dBAKER
_dBWKUK
_dUKM
_dXMA
_dNBU
_dDLC
_erda
041 1 _aeng
_hfre
082 0 0 _a572.8633
_222
_bR.S.D
100 1 _aRobin, Stéphane,
_d1965-,
_97637
_eauthor.
240 1 0 _aADN, mots, et modéles.
_lEnglish
245 1 0 _aDNA, words and models /
_cStéphane Robin, François Rodolphe, Sophie Schbath.
264 1 _aCambridge, UK ;
_aNew York :
_bCambridge University Press,
_c2005
300 _axx, 138 pages :
_billustrations ;
_c24 cm
336 _2rdacontent
_atext
337 _2rdamedia
_aunmediated
338 _2rdacarrier
_avolume
504 _aIncludes bibliographical references (pages 134-136) and index.
505 0 _aIntroduction. The context -- Randomness and models -- A bit of biology -- Simple models for biological sequences. Why a model? -- Permutation model -- Bernoulli model -- Introduction to Markov chain models. Assumptions -- Markov chain order 1 -- Markov chain order m -- Estimation of the parameters -- Taking heterogeneities into account. Phased chains -- Piecewise homogeneous Markov chains -- Translation conditional models -- Statistical properties of word occurrences. Count -- Positions and distances -- Distribution along the sequence -- Words with unexpected frequencies. Exact distribution and approximations -- Influence of the model -- Over-representations of Chi sites in E. coli and H. influenzae -- Under-representation of palindromes of length 6 in E. coli and in the phage Lambda -- Words with unexpected locations. Chi sites in the genome of H. influenzae -- Distribution of palindromes in E. coli's genome -- Detection of promoter sites in B. subtilis -- The last word.
650 0 _aGenetics
_xMathematical models.
650 0 _aMarkov processes.
700 1 _aRodolphe, François.
_97640
_eauthor.
700 1 _aSchbath, Sophie,
_d1969-,
_97641
_eauthor.
856 4 2 _3Publisher description
_uhttp://www.loc.gov/catdir/enhancements/fy0632/2005047088-d.html
856 4 1 _3Table of contents only
_uhttp://www.loc.gov/catdir/enhancements/fy0632/2005047088-t.html
906 _a7
_bcbc
_corignew
_d1
_eocip
_f20
_gy-gencatlg
942 _2ddc
_cBK