000			02961nam a22003618i 4500
999			_c2083 _d2083
001			14444067
005			20190718131506.0
008			060710s2007 stk f b 001 0 eng d
010			_a 2006045095
020			_a9780443101083
020			_a0443101086
020			_a9780443101076 (International ed.)
020			_a0443101078 (International ed.)
040			_aDNLM/DLC _cDLC _erda
082	0	0	_a615.19 _222 _bP.
245	0	0	_aAulton's Pharmaceutics : _bthe design and manufacture of medicines / _cedited by Michael E. Aulton.
250			_aThird edition.
264		1	_aEdinburgh ; _aNew York : _bChurchill Livingstone, _c2007.
300			_ax, 717 pages : _bIllustrations ; _c25 cm
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
504			_aIncludes bibliographical references and index.
505	0		_a What is 'pharmaceutics'? Design of dosage forms PART ONE: SCIENTIFIC PRINCIPLES OF DOSAGE FORM DESIGN *Dissolution and solubility *Properties of solutions *Rheology *Surface and interfacial phenomena *Disperse systems *Kinetics of product stability PART TWO: PARTICLE SCIENCE AND POWDER TECHNOLOGY *Solid-state properties *Particle size analysis *Particle size reduction *Particle size separation *Mixing *Powder flow. PART THREE: PHARMACEUTICAL MICROBIOLOGY AND STERILIZATION *Fundamentals of microbiology *Pharmaceutical applications of microbiological techniques *Action of physical and chemical agents on microorganisms *Principles of sterilization *Sterilization in practice PART FOUR: BIOPHARMACEUTICAL PRINCIPLES OF DRUG DELIVERY *Introduction to biopharmaceutics *Gastrointestinal tract - physiology and drug absorption *Bioavailability - physicochemical and dosage form factors *Assessment of biopharmaceutical properties *Dosage regimens PART FIVE: DOSAGE FORM DESIGN AND MANUFACTURE *Pharmaceutical preformulation *Solutions *Clarification *Suspensions and emulsions *Powders and granules *Granulation *Drying *Tablets and compaction *Modified-release peroral dosage forms *Coating of tablets and multiparticulates *Hard gelatin capsules *Soft gelatin capsules *Pulmonary drug delivery *Nasal drug delivery *Transdermal drug delivery *Wound dressings *Rectal and vaginal drug delivery *Delivery of pharmaceutical proteins *Packs and packaging *Microbial contamination, spoilage and preservation of medicines *Product stability and stability testing *Pharmaceutical plant design *Heat transfer and the properties and use of steam
520			_a Pharmaceutics is the art of pharmaceutical preparations. It encompasses design of drugs, their manufacture and the elimination of micro-organisms from the products. This book encompasses all of these areas
650		0	_aDrugs _xDosage forms.
650		0	_aDrugs _xDesign.
650	1	2	_aDosage Forms.
650	2	2	_aBiopharmaceutics.
650	2	2	_aDrug Design.
700	1		_aAulton, Michael E., _eauthor.
942			_cBK _2ddc