000			02152nam a22002897i 4500
005			20190718131635.0
008			100914s2008 ii||||| |||| 00| 0 eng d
020			_a8123913079
040			_aFUE _erda
082	0	4	_221 _a615.7 _bK.J.B
100	1		_aKulkarni, Jayant S. _98874
245	1	0	_aBiopharmaceutics and pharmacokinetics / _cJayant S. Kulkarni, A.P. Pawar, V.P. Shedbalkar.
264		1	_aNew Delhi : _bCBS publishers and distributors, _c[2008]
264		4	_ccopyright 2008
300			_ax, 301 pages ; _c24 cm.
336			_atext _btxt _2rdacontent
337			_aunmediated _bn _2rdamedia
338			_avolume _bnc _2rdacarrier
500			_aIncludes index.
505	2		_aAbsorption of drugs -- distribution of drugs -- drug metabolism (bio-transformation) -- excretion -- prodrugs -- pharmaceutics - basic considerations -- one compartment mode -- multi-compartment model -- nonlinear pharmaceutics -- non- compartmental analysis -- applications pharmaceutics -- bio-equivalence -- introduction to bioanalysis
520			_aBiopharmaceutics and Pharmacokinetics deals with what body does to the drug. In this book, along with the fundamentals of absorption, distribution, metabolism and excretion, current topics such as in vitro systems have also been introduced. In case of pharmacokinetics models, authors have tried to keep mathematical part simpler and minimal. This book also introduces "non compartmental models", which are gaining increasing importance in the analysis of pharmacokinetic data. In the chapter "applications of pharamacokinetics", newer concepts such as chronopharmacokinetics have been introduced. Bioequivalence is covered in last two chapters. Besides clinical aspects of bioequivalence, some of the important aspects of bioanalysis have also been introduced. The regulatory aspect of bioequivalence has also been covered. Thus an attempt has been made to cover all the basic aspects of biopharmaceutics and pharmacokinetics in a reader-friendly manner
650		0	_aBiopharmaceutics.
650		0	_aPharmacokinetics.
700	1		_aPawar, A.P. _98877
700	1		_aShedbalkar, V.P. _98878
942			_cBK _2ddc
999			_c2156 _d2156