000			03717nam a22002777i 4500
999			_c5682 _d5682
005			20201026151135.0
008			120228s2010 ii ||||| |||| 001 0 eng d
020			_a9788184487415
040			_aEG-NcFUE _erda
082			_a617.6 _bP.G.G _221
100	1		_aPal, GP. _923612 _eauthor.
245	1	0	_aGenetics in dentistry / _cGP. Pal, Mahato Niladri Kumar.
264			_aNew Delhi : _bJaypee, _c2010
300			_a198 pages : _billustrations ; _c28 cm
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
500			_aIncludes index.
505	0		_aSECTION 1: ESSENTIALS OF HUMAN GENETICS 1. Introduction and Mendel’s Laws of Inheritance -- Definition of genetics -- Divisions of genetics -- Classification of genetic diseases -- Genetics in dentistry -- Mendel and his laws of inheritance -- The pea plants experiments -- Mendel’s laws -- 2. Chromosomes and their Classification -- Introduction to human chromosomes -- Classification of chromosomes and analysis -- Chromosomal analysis -- Sex chromatin -- Lyon’s hypothesis -- 3. Structure of DNA and RNA -- Structure and packaging of DNA -- Replication of DNA -- Mitochondrial DNA -- Structure of ribonucleic acid (RNA) -- 4. Structure and Function of Genes -- Molecular structure of genes -- Genetic code --Transcription -- Alternative splicing -- Translation -- Gene expression and its regulation -- Genetic mutation, its types and mutagens -- Mechanism of DNA repair -- 5. Chromosomal Anomalies -- Numerical anomalies -- Numerical abnormalities of autosomes -- Structural anomalies -- CRI-DU-chat syndrome-- Existence of different cell lines (mosaicism/chimerism) -- 6. Patterns of Inheritance and Disorders of Genes -- Single gene (mendelian/monogenic) inheritance -- Mitochondrial inheritance -- Multiple genes (polygenic/multifactorial) inheritance -- Some important terms commonly used in relation to genetic inheritance -- 7. Genetics of Immunity -- Concept of immune mechanisms -- Structure of immunoglobulins -- Immunodeficiency disorders -- Transplantation of tissues -- 8. Molecular Control of Development -- Molecular processes in development -- A brief account of the molecular control of early embryonic development
505	0		_aSECTION 2: GENETICS IN DENTISTRY -- 9. Methods of Genetic Analysis -- Identification of heritable dental pathology -- Segregation analysis -- Twin studies -- Linkage analysis -- Association studies -- 10. Genetics of Developmental Disorders of Teeth -- Molecular (genetic) control of development of tooth -- Tooth agenesis -- Supernumerary teeth or hyperdontia -- Taurodontism -- Amelogenesis imperfecta -- Dentinogenesis imperfecta -- Dentine dysplasia -- Hypophosphatasia -- 11. Genetics of Craniofacial Disorders and Syndromes -- Molecular regulation of the development of face -- Ectodermal dysplasia -- Holoprosencephaly -- Mandibulofacial dysostosis (Treacher Collins–Franceschetti syndrome) -- Cleidocranial dysplasia -- Apert syndrome (Acrocephalosyndactyly) -- Crouzon syndrome (Craniofacial dysostosis) -- Pfeiffer syndrome -- Cherubism -- Van Der Woude syndrome -- Gorlin–Goltz syndrome -- Waardenburg syndrome (WS) -- Osteogenesis imperfecta -- Down’s syndrome -- Achondroplasia 12. Genetics of Cleft Lip and Cleft Palate -- 13. Genetics of Dental Caries -- 14. Genetics of Periodontitis -- 15. Genetics of Malocclusion -- 16. Genetics of Cancer -- SECTION 3: ADVANCEMENTS IN GENETICS -- 17. Gene Therapy in Dentistry -- 18. Techniques Used in Genetics -- Index
650		0	_aDentistry _923613
650		0	_aGenetics _923614
700			_aMahato, Niladri Kumar _923615 _eauthor.
942			_cBK _2ddc