000			03233cam a22003854a 4500
999			_c6832 _d6832
001			15656281
005			20190512125006.0
008			090310s2010 ne a b 001 0 eng
010			_a 2009009659
020			_a9780123749994 (pbk. : alk. paper)
020			_a0123749999 (pbk. : alk. paper)
040			_aDNLM/DLC _cDLC _dNLM _dC#P _dBWX _dYDXCP _dDLC _erda
050	0	0	_aRA1057.55 _b.B883 2010
082	0	0	_a614.1 _bB.J.F _222
100	1		_aButler, John M. _q(John Marshall), _d1969- _933229
245	1	0	_aFundamentals of forensic DNA typing / _cJohn M. Butler.
260			_aAmsterdam ; _aBoston : _bAcademic Press/Elsevier, _cc2010.
300			_axviii, 500 p. : _bill. ; _c24 cm.
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
500			_aBased on author's Forensic DNA typing : biology & technology behind STR markers. c2001.
504			_aIncludes bibliographical references and index.
505	0		_aOverview and history of DNA typing -- Basics of DNA biology and genetics -- Historical methods -- Sample collection, storage, and characterization -- DNA extraction -- DNA quantitation -- DNA amplification (the polymerase chain reaction) -- Short tandem repeat markers -- Fundamentals of DNA separation and detection -- STR genotyping and data interpretation -- Statistical interpretation : evaluating the strength of forensic DNA evidence -- DNA databases -- Quality assurance -- Forensic challenges : degraded DNA, mixtures, and LCN -- Additional loci and nonhuman DNA testing -- Lineage markers : Y chromosome and mtDNA testing -- Applications of DNA typing -- Future trends.
520			_aFundamentals of Forensic DNA Typing is written with a broad viewpoint. It examines the methods of current forensic DNA typing, focusing on short tandem repeats (STRs). It encompasses current forensic DNA analysis methods, as well as biology, technology and genetic interpretation. This book reviews the methods of forensic DNA testing used in the first two decades since early 1980’s, and it offers perspectives on future trends in this field, including new genetic markers and new technologies. Furthermore, it explains the process of DNA testing from collection of samples through DNA extraction, DNA quantitation, DNA amplification, and statistical interpretation. The book also discusses DNA databases, which play an important role in law enforcement investigations. In addition, there is a discussion about ethical concerns in retaining DNA profiles and the issues involved when people use a database to search for close relatives. Students of forensic DNA analysis, forensic scientists, and members of the law enforcement and legal professions who want to know more about STR typing will find this book invaluable.
650		0	_aDNA fingerprinting. _933230
650		0	_aForensic genetics. _933231
650	1	2	_aDNA Fingerprinting _xmethods. _933232
650	2	2	_aDNA _xphysiology. _933233
650	2	2	_aForensic Medicine _xmethods. _933234
700	1		_aButler, John M. _q(John Marshall), _d1969- _tForensic DNA typing. _933235
856			_3Abstract _uhttp://repository.fue.edu.eg/xmlui/handle/123456789/1652
942			_cBK _2ddc