000 01359cam a2200289 i 4500
999 _c7295
_d7295
005 20201006120923.0
008 121022s2012 sw a 000 0 eng
020 _a9781466560314
020 _a9197945234
020 _a9789197945233
040 _aEG-NcFUE
_erda
082 0 4 _222
_a615.7
_bG.J.Q
100 1 _aGabrielsson, Johan.
_eauthor.
245 1 0 _aQuantitative pharmacology :
_ban introduction to integrative pharmacokinetic-pharmacodynamic analysis /
_cby Johan Gabrielsson & Stephan Hjort.
264 1 _aSweden :
_bSwedish Pharmaceutic,
_c2012.
300 _a263 pages :
_bcolor illustartions ;
_c25 cm
336 _2rdacontent
_atext
337 _2rdamedia
_aunmediated
338 _2rdacarrier
_avolume
504 _aIncludes bibliographical references.
505 0 _aCh. 1. Introduction -- What is PK/PD and quantitative pharmacology -- ch. 2. Principles of kinetics from a pharmacodynamic point of view -- ch. 3. Principles of plasma protein binding -- ch. 4. Principles of dose, time and flow dependencies -- ch. 5. Principles of rapid concentration-response equilibria -- ch. 6. Time delays between plasma concentration and response -- ch. 7. Principles of inter-species scaling.
650 _aPharmacokinetics.
700 1 _aHjorth, Stephan.
_eauthor.
942 _cBK
_2ddc