000			03233cam a22004094a 4500
999			_c7376 _d7376
001			14964502
005			20190509110122.0
008			070809s2008 nyua b 001 0 eng
010			_a 2007033181
020			_a9780824758097 (hb : alk. paper)
020			_a0824758099 (hb : alk. paper)
040			_aDNLM/DLC _cDLC _dDLC _erda
050	0	0	_aRS201.S57 _bP74 2008
082	0	0	_a615.19 _222 _bP
245	0	0	_aPreformulation solid dosage form development / _cedited by Moji C. Adeyeye, Harry G. Brittain.
260			_aNew York : _bInforma Healthcare USA, _cc2008.
300			_aviii, 596 p. : _bill. ; _c24 cm.
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
440		0	_aDrugs and the pharmaceutical sciences ; _v178
504			_aIncludes bibliographical references and index.
505	0		_aAccelerating the course of preliminary-preformulation through prediction of molecular physical properties and integrated analytical data management / Robert S. DeWitte, Michel Hachey, and Harry G. Brittain -- Prediction of crystallographic characteristics / Steve Spanton -- Salt selection for pharmaceutical compounds / Sherif I. Badawy, Miriam K. Franchini, and Munir A. Hussain -- Intelligent preformulation design and predictions using artificial neural networks / Nkere K. Ebube -- Developing a profile of the active pharmaceutical ingredient / Harry G. Brittain -- Particle morphology and characterization in preformulation / Alan Rawle -- Preparation and identification of polymorphs and solvatomorphs / Harry G. Brittain -- X-ray diffraction methods for the characterization of solid pharmaceutical materials / Jean Blachere and Harry G. Brittain -- Spectroscopic methods for the characterization of drug substances / Harry G. Brittain -- Thermal analysis and calorimetric methods for the characterization of new crystal forms / Dennette Murphy Shelley Rabel -- Solubility methods for the characterization of new crystal forms / Harry G. Brittain -- Overview of the solid dosage form preformulation program / Harry G. Brittain -- Drug-excipient interactions appropriate to solid dosage forms / Moji Christianah Adeyeye -- Methods for the determination of the physical and chemical stability of a new solid dosage form / Harry G. Brittain -- Dissolution testing / Chuck Collins and George Wong -- Structure, content, and format of the preformulation report / Ram N. Gidwani -- Significance of drug substance physicochemical properties in regulatory quality by design / Sau Lawrence Lee, Andre S. Raw, and Lawrence Yu.
650		0	_aSolid dosage forms. _928023
650		0	_aDrug development.
650		0	_aPharmaceutical chemistry.
650	1	2	_aChemistry, Pharmaceutical.
650	2	2	_aDosage Forms.
650	2	2	_aPharmaceutical Preparations _xchemical synthesis.
700	1		_aAdeyeye, Moji C.
700	1		_aBrittain, H. G.
856	4	1	_3Table of contents only _uhttp://www.loc.gov/catdir/toc/ecip0725/2007033181.html
856	4	2	_3Publisher description _uhttp://www.loc.gov/catdir/enhancements/fy0740/2007033181-d.html
856	4	2	_3Abstract _uhttp://repository.fue.edu.eg/xmlui/handle/123456789/1671
942			_cBK _2ddc