000			02926cam a22003857i 4500
999			_c7392 _d7392
001			16800016
005			20210103105307.0
008			110527s2011 nyua b 001 0 eng d
010			_a 2011930757
020			_a9781617791789 (alk. paper)
020			_a1617791784 (alk. paper)
040			_aYDXCP _cYDXCP _dRML _dCUX _dBWX _dUKMGB _dCDX _dCAI _dDLC _erda
050	0	0	_aQP552.G16 _bM48 2011
082	0	4	_222 _a572.696 _bM
245	0	0	_aMethods for the discovery and characterization of G protein-coupled receptors / _cedited by Craig W. Stevens.
264		1	_aNew York : _bHumana Press, _cc2011.
264		4	_cc2011.
300			_axiii, 428 pages. : _billustrations. ; _c26 cm.
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
490	1		_aNeuromethods ; _v60
504			_aIncludes bibliographical references and index.
505	0	0	_tIn silico identification of novel G protein-coupled receptors / _tAlternative pre-mRNA splicing of G protein-coupled receptors / _tDetecting polymorphisms in G protein-coupled receptor genes / _tRegulation of the transcription of G protein-coupled receptor genes / _tDeciphering the evolution of G protein-coupled receptors in vertebrates / _tNew approach to visualize endogenously expressed G protein-coupled receptors in tissues and living cells / _tPosttranslational regulation of G protein-coupled receptors / _tDiscovering G protein-coupled receptor motifs mediating export from the endoplasmic reticulum / _tIdentifying G protein-coupled receptor escorts, chaperones, and intracellular tethers regulating receptor density at the cell surface / _tNovel method for determining the kinetics of G protein-coupled receptor plasma membrane expression / _tCharacterizing the pharmacology of G protein-coupled receptors in transfected cell lines / _tNovel assay technologies for the discovery of G protein-coupled receptor drugs / _tDiscovering cell type-specific patterns of G protein-coupled receptor phosphorylation / _tQuantifying allosteric modulation of G protein-coupled receptors / _tExperimental designs for the study of receptor-receptor interactions / _tElucidating agonist-selective mechanisms of G protein-coupled receptor desensitization / _tDetecting the role of arrestins in G protein-coupled receptor regulation / _tCharacterizing molecular mobility and membrane interactions of G protein-coupled receptors / _tUsing RNA interference to downregulate G protein-coupled receptors / _tUpregulating G protein-coupled receptors with receptor antagonists /
650		0	_aG proteins.
650		0	_aG proteins _xReceptors.
650		2	_aGTP-Binding Proteins.
650		2	_aReceptors, G-Protein-Coupled.
700	1		_aStevens, Craig W. _eeditor
830		0	_aNeuromethods ; _v60.
856			_3Abstract _uhttp://repository.fue.edu.eg/xmlui/handle/123456789/2752
942			_cBK _2ddc