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_c7393 _d7393 |
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| 001 | 13585075 | ||
| 005 | 20201223143119.0 | ||
| 008 | 040507s2005 caua b 001 0 eng | ||
| 010 | _a 2004043051 | ||
| 020 | _a1891389289 (alk. paper) | ||
| 040 |
_aDLC _cDLC _dYDX _dBAKER _dDLC _erda |
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| 050 | 0 | 0 |
_aQH447 _b.B57 2005 |
| 082 | 0 | 0 |
_a572.86 _222 _bB.R.I |
| 100 | 1 |
_aBlake, R. D. _q(Richard D.), _d1932- _eAuthor |
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| 245 | 1 | 0 |
_aInformational biopolymers of genes and gene expression : _bproperties and evolution / _cR.D. Blake. |
| 264 | 1 |
_aSausalito, Calif. : _bUniversity Science Books, _cc2005. |
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| 264 | 4 | _cc2005. | |
| 300 |
_axxii, 778 pages. : _billustrations. ; _c26 cm. |
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| 336 |
_2rdacontent _atext |
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| 337 |
_2rdamedia _aunmediated |
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| 338 |
_2rdacarrier _avolume |
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| 504 | _aIncludes bibliographical references and index. | ||
| 505 | 0 | _aChapter 1: Introduction to theInformational Biopolymers.1.1 Proteins.1.2 NucleicAcids.1.3 The Roles of the Informational Biopolymers in the Dissemination ofGenetic Information.1.4 The Cellular Imperative.Chapter 2: Forces Within and BetweenBiopolymers.2.1 Conformational Potential Energy.2.2. Dispersionand Exclusion Effects.2.3. IonicInteractions.2.4. DipoleInteractions.2.5. van derWaals Forces.2.6. HydrogenBonds.2.7. HydrophobicBonds.2.8. StackingInteractions.2.9. ModelingStructures by Computational Molecular Mechanics.Chapter 3: Proteins.3.1 Amino Acids3.2 ThePeptide Backbone.3.3 Secondary Structures..3.4 Thermodynamics of the a-Helix.3.5 Tertiaryand Quaternary Structures.3.6. ProteinFolding.3.7. Evolutionary Relationships from PrimarySequences.Chapter 4: Covalent Features of theNucleic Acids.4.1. Nucleotide Sugar4.2. NucleotideBase.4.3. The N-Glycosidic Bond.4.4. PhosphoesterBond.4.5. Pyrimidineand Nucleotide CofactorsChapter 5: Structure, Synthesis andFunction of RNA5.1. The Preponderance of Ribosomal, Transfer, and Small Nuclear RNA in Cells.5.2. Primary Structures of RNA5.3. Secondary Structures of RNAs.5.4. Tertiary Structures of RNAs.5.5. Protein-RNA Interactions.5.6 The Biosynthesis of RNAs: Transcription.5.7. The Participation of RNAs in Protein Synthesis. Chapter 6: Secondary Structure ofDuplex DNA.6.1. Contributions of Fiber Diffraction to Our Knowledge of DNA Structure.6.2. Prelude to the Watson-Crick Douuble Helix.6.3. Refined and Archetypal Structures. 6.4. Structural Features Common to All Nucleic Acid Helices.6.5. Structures From Single-Crystal Diffraction Analysis.6.6. Structure in Solutions.6.7. Hydrogen Bonding in an Aqueous Environment.6.8. MolecularDynamics of DNA.6.9. Denaturationand the Thermodynamics of DNA Stability.6.10. Higher Organization of DNA.6.11. Macromolecular Structure.Chapter 7: Primary Sequences of DNA. 7.1. BaseCompositions of Prokaryotic DNAs7.2. Base Compositions of Eukaryotic DNAs.7.3. Dinucleotide (Nearest Neighbor) Frequencies7.4. Sequence Complexity.7.5. Primary Sequences in Prokaryotes.7.6. Primary Sequence Elements in Eukaryotes.7.7. Satellite DNA and Repetitive Sequences.7.8. PrimarySequences of Mitochondrial DNA.7.9. DeterminingEvolutionary Relationships from Primary Sequences. Chapter 8: Interactions of Waterand Cations With DNA, Integral Components of the Native Conformation. 8.1. The UnusualCharacter of Water.8.2. Hydration ofElectrolytes.8.3. Interactionsof Hydrated Ions in Solution8.4. MacroscopicStudies of DNA Hydration.8.5. MicroscopicStudies of DNA Hydration. Single Crystal Diffraction.8.6. Interactionsof Cations with DNA.Chapter 9: Structures and Functional Interactions of Proteins with DNA.9.1. Modes ofInteraction.9.2 Methodsof Analysis. 9.3. Principles of Sequence-Specific DNA Binding Proteins.9.4. DNA-BindingProteins of the Structural Class.9.5. DNA-BindingProteins of the Enzymatic Class.9.6. DNA-BindingProteins of the Regulatory Class.Chapter 10. Cellular Replication of DNA.10.1 Stagesof Replication.10.2. Origin Locus of Replication.10.3. Condensation of dNTP and Elongation of DNA.10.4. Auxiliary Replicative Processes.10.5. Replication of the Ends of Linear Eukaryotic DNA by Telomerase.Chapter 11: Mutations and Unscheduled Decay, Reactivity and Interactions of DNA.11.1.Mutations.11.2. Point Mutations.11.3. Relative Rates of Point Mutation11.4. Molecular Basis of Mutagenesis. 11.5. Reactions withEndogenous Agents.11.6. Reactions of Exogenous Agents with DNA.Chapter 12: Repair and Recombination of DNA.12.1. Enzymesthat Serve Several Functional Roles Including Repair.12.2. Multiple Pathways for the Repair of Damage Caused by UV Radiation.12.3. Mismatch Repair.12.4. Excision Repair.12.5. Direct Reversal of Certain Lesions.12.6. The SOS Repair System.12.7. Recombination and Recombination Repair.Chapter 13: Prebiotic Origins.13.1 The PhysicalAge of the Universe.13.2. Formation of Earth.13.3. Age ofChemistry.13.4. Thermodynamic Precepts for Origins and Order. Dissipative Processes.13.5. Hypercycles.13.6. Age of Abiotic Chemistry, Synthesis of Alpha and Beta Molecules.13.7. Synthesis of Gamma Monomeric Units of D-Ribose by Abiotic Means.13.8. Beta Monomeric Units of Ribose Analogs.13.9. The Age of Prebiotic Chemistry.13.10. The RNA World. | |
| 650 | 0 | _aGenes. | |
| 650 | 0 | _aGene expression. | |
| 650 | 0 | _aInformation theory in biology. | |
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